DrugDashboards

Xpovio

selinexor · SELINEXOR 10 mg/1 · Tablet, Film Coated · Oral · Karyopharm Therapeutics Inc.

NDC 72237-0106-01 · 4 BLISTER PACK in 1 CARTON / 4 TABLET, FILM COATED in 1 BLISTER PACK · NDA · View full market →

The short version

Just 2 companies supply this market — thin enough that a single exit would be felt immediately.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Part D plans paid (avg)$6,013.16per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$2,200.58per unitnegotiated price across 5,496 plans — before rebates · Apr 1, 2026
  • List price (WAC, as filed)$34,722.00per packageKaryopharm Therapeutics Inc. · Jan 1, 2026

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$2,200.58per unit
middle half $2,174.99$2,263.61 · 5,496 plans · Apr 1, 2026
Est. net of rebates
$1,320.35–$1,650.43
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
100%of plans cover it
tier 5 · prior auth 98% · step therapy 0% · qty limit 78%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 4 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed
$34,722.00
Reported to Texas DSHS · 2026 annual filing · Karyopharm Therapeutics, Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$360,769
11 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Is this a "specialty" drug?

There's no legal definition — it meets 3 of 6 public criteria. Why that matters →

  • Part D specialty tier · median tier 5 across plans
  • Costs ≥ $950/fill · avg $28,651.69 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA212306
TE code
Approval date
Jul 3, 2019
Patents / exclusivity
66 patents, 8 exclusivities
TypeNumber / codeExpires
exclusivityODE*Dec 18, 2027
exclusivityODE*Dec 18, 2027
exclusivityODE*Dec 18, 2027
exclusivityODE*Dec 18, 2027
exclusivityODE-346Dec 18, 2027
exclusivityODE*Dec 18, 2027
exclusivityODE-310Jun 22, 2027
exclusivityODE-257Jul 3, 2026
patent11753401Aug 14, 2035
patent11753401Aug 14, 2035
patent11753401Aug 14, 2035
patent11807629Aug 14, 2035

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of selinexor (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
Catalent Pharma Solutions, LLCSELINEXOR 20 mg/1Jul 15, 2026Sep 2, 2026
Catalent Pharma Solutions, LLCSELINEXOR 80 mg/1Jul 15, 2026Sep 2, 2026
Catalent Pharma Solutions, LLCSELINEXOR 10 mg/1Jul 15, 2026Sep 2, 2026
Karyopharm Therapeutics Inc.SELINEXOR 40 mg/1Jul 15, 2026Sep 2, 2026
Karyopharm Therapeutics Inc.SELINEXOR 50 mg/1Jul 15, 2026Sep 2, 2026
Karyopharm Therapeutics Inc.SELINEXOR 60 mg/1Jul 15, 2026Sep 2, 2026
Karyopharm Therapeutics Inc.SELINEXOR 80 mg/1Jul 15, 2026Sep 2, 2026
Karyopharm Therapeutics Inc.SELINEXOR 10 mg/1Jul 15, 2026Sep 2, 2026
Karyopharm Therapeutics Inc.SELINEXOR 20 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Xpovio — NDC 72237-0106-01," retrieved September 3, 2026, https://drugdashboards.com/drug/72237010601.

Free to cite with attribution — see how the data is put together.