DrugDashboards

Piperacillin and Tazobactam

piperacillin sodium and tazobactam sodium · PIPERACILLIN SODIUM 3 g/15mL; TAZOBACTAM SODIUM .375 g/15mL · Injection, Powder, For Solution · Intravenous · Civica, Inc.

NDC 72572-0573-10 · 10 VIAL, SINGLE-DOSE in 1 CARTON / 15 mL in 1 VIAL, SINGLE-DOSE · ANDA · View full market →

The short version

Just 2 companies supply this market — thin enough that a single exit would be felt immediately. The price has held steady around $3.49 per unit over the past year. Put together: worth watching — several of the pressures that precede supply trouble are present at once. Historically, drugs in this position went on to a new shortage within 90 days about 0.5% of the time — roughly 4× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$3.49per EAinvoice-surveyed acquisition cost · Jan 21, 2026
  • Medicare Part B pays (ASP+6%)$1.22per billing unit (1.125 GM)HCPCS J2543 · Jul 1, 2026

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$2.00$4.00$6.00Jul 2024Jan 2026$3.49
20 price points · per EA · last surveyed Jan 21, 2026Source: CMS NADAC

Estimated fill cost

WAC per package, as filed
$40.90
Reported to Texas DSHS · 2025 annual filing · Civica, Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicare Part B (ASP)

Payment limit per 1.125 GM
$1.218
HCPCS J2543 · Jul 1, 2026 quarter · typically ASP + 6%

Medicaid spend (2025)

$74
135 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

30● Elevated risk

The score is counting real pressure here. One of these alone is routine; it’s the combination that makes this market worth watching.

  • 2 active manufacturers+20
  • sterile injectable+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.5%chance of a new FDA shortage posting for piperacillin sodium and tazobactam sodium (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 4× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA065523
TE code
AP
Approval date
May 31, 2011
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of piperacillin sodium and tazobactam sodium (Injection, Powder, For Solution)

LabelerStrengthFirst seenLast seen
Fresenius Kabi USA, LLCPIPERACILLIN SODIUM 36 g/180mL; TAZOBACTAM SODIUM 4.5 g/180mLJul 15, 2026Sep 3, 2026
Civica, Inc.PIPERACILLIN SODIUM 3 g/15mL; TAZOBACTAM SODIUM .375 g/15mLJul 15, 2026Sep 2, 2026
Civica, Inc.PIPERACILLIN SODIUM 4 g/20mL; TAZOBACTAM SODIUM .5 g/20mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Piperacillin and Tazobactam — NDC 72572-0573-10," retrieved September 3, 2026, https://drugdashboards.com/drug/72572057310.

Free to cite with attribution — see how the data is put together.