The short version
12 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Valproic Acid · VALPROIC ACID 250 mg/5mL · Solution · Oral · NorthStar Rx LLC
NDC 72603-0253-01 · 473 mL in 1 BOTTLE · ANDA · View full market →
12 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Matched to CMS's representative package for this drug (NDC 00121-0675-85) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 7 quarters since 2024.
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Not scored — fragility is computed for NADAC-priced NDCs.
OAI inspection at a producing facility (24 months) · sole-source market · price up 2% YoY
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| PAI Holdings, LLC dba PAI Pharma | VALPROIC ACID 250 mg/5mL | Jul 15, 2026 | Sep 3, 2026 |
| Remedyrepack Inc. | VALPROIC ACID 250 mg/5mL | Jul 15, 2026 | Sep 3, 2026 |
| American Health Packaging | VALPROIC ACID 500 mg/10mL | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | VALPROIC ACID 250 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| ANI Pharmaceuticals, Inc. | VALPROIC ACID 250 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | VALPROIC ACID 250 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Chartwell Governmental & Specialty RX, LLC. | VALPROIC ACID 500 mg/10mL | Jul 15, 2026 | Sep 2, 2026 |
| Chartwell Governmental & Specialty RX, LLC. | VALPROIC ACID 250 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Chartwell RX, LLC | VALPROIC ACID 500 mg/10mL | Jul 15, 2026 | Sep 2, 2026 |
| Chartwell RX, LLC | VALPROIC ACID 250 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Kesin Pharma Corporation | VALPROIC ACID 250 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | VALPROIC ACID 250 mg/5mL | Aug 5, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | VALPROIC ACID 500 mg/10mL | Aug 5, 2026 | Sep 2, 2026 |
| NorthStar Rx LLC | VALPROIC ACID 250 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| PAI Holdings, LLC dba PAI Pharma | VALPROIC ACID 500 mg/10mL | Jul 15, 2026 | Sep 2, 2026 |
| Quagen Pharmaceuticals Llc | VALPROIC ACID 250 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Xttrium Laboratories Inc. | VALPROIC ACID 250 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Valproic Acid — NDC 72603-0253-01," retrieved September 3, 2026, https://drugdashboards.com/drug/72603025301.
Free to cite with attribution — see how the data is put together.