The short version
Only one company currently supplies this market — there is no backup if it stumbles.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Mucinex 12HR Cold and Fever Multi-Symptom
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin · DEXTROMETHORPHAN HYDROBROMIDE 30 mg/1; NAPROXEN SODIUM 110 mg/1; GUAIFENESIN 600 mg/1 · Tablet, Extended Release · Oral · Reckitt Benckiser LLC
NDC 72854-0001-16 · 2 BLISTER PACK in 1 CARTON / 8 TABLET, EXTENDED RELEASE in 1 BLISTER PACK · NDA · View full market →
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Regulatory
- Application
- NDA217338
- TE code
- —
- Approval date
- Dec 22, 2025
- Patents / exclusivity
- 3 patents, 0 exclusivities
| Type | Number / code | Expires |
|---|---|---|
| patent | 12257218 | Oct 11, 2036 |
| patent | 12370189 | Oct 11, 2036 |
| patent | 11278506 | Oct 11, 2036 |
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin (Tablet, Extended Release)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Reckitt Benckiser LLC | DEXTROMETHORPHAN HYDROBROMIDE 30 mg/1; NAPROXEN SODIUM 110 mg/1; GUAIFENESIN 600 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Reckitt Benckiser LLC | DEXTROMETHORPHAN HYDROBROMIDE 30 mg/1; NAPROXEN SODIUM 600 mg/1; GUAIFENESIN 110 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Reckitt Benckiser LLC | DEXTROMETHORPHAN HYDROBROMIDE 30 mg/1; GUAIFENESIN 600 mg/1; NAPROXEN SODIUM 110 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Mucinex 12HR Cold and Fever Multi-Symptom — NDC 72854-0001-16," retrieved September 3, 2026, https://drugdashboards.com/drug/72854000116.
Free to cite with attribution — see how the data is put together.