The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Mucinex Nightshift Cold and Flu Maximum Strength
acetaminophen, dextromethorphan hydrobromide, and triprolidine hydrochloride · ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; TRIPROLIDINE HYDROCHLORIDE 1.25 mg/1 · Tablet, Coated · Oral · Reckitt Benckiser LLC
NDC 72854-0233-20 · 2 BLISTER PACK in 1 CARTON / 10 TABLET, COATED in 1 BLISTER PACK · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- M012
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of acetaminophen, dextromethorphan hydrobromide, and triprolidine hydrochloride (Tablet, Coated)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| RB Health (US) LLC | ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; TRIPROLIDINE HYDROCHLORIDE 1.25 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| RB Health (US) LLC | DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; ACETAMINOPHEN 325 mg/1; TRIPROLIDINE HYDROCHLORIDE 1.25 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Reckitt Benckiser LLC | ACETAMINOPHEN 325 mg/1; DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1; TRIPROLIDINE HYDROCHLORIDE 1.25 mg/1 | Jul 15, 2026 | Aug 31, 2026 |
| RB Health (US) LLC | DEXTROMETHORPHAN HYDROBROMIDE 325 mg/1; ACETAMINOPHEN 10 mg/1; TRIPROLIDINE HYDROCHLORIDE 1.25 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Mucinex Nightshift Cold and Flu Maximum Strength — NDC 72854-0233-20," retrieved September 3, 2026, https://drugdashboards.com/drug/72854023320.
Free to cite with attribution — see how the data is put together.