The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
oxycodone hydrochloride and acetaminophen
oxycodone hydrochloride and acetaminophen · OXYCODONE HYDROCHLORIDE 10 mg/5mL; ACETAMINOPHEN 300 mg/5mL · Solution · Oral · FH2 Pharma LLC
NDC 72887-0648-12 · 120 mL in 1 BOTTLE, PLASTIC · ANDA · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 72245-0648-50) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$11.46per unit
middle half $11.46–$11.56 · 99 plans · Jul 1, 2024
Est. net of rebatesⓘ
≈ $11.46
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
—of plans cover it
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 3 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Estimated fill cost
WAC per package, as filed
$2,625.00
Reported to Texas DSHS · 2026 annual filing · FH2 Pharma
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- ANDA202142
- TE code
- —
- Approval date
- Nov 27, 2018
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of oxycodone hydrochloride and acetaminophen (Solution)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| FH2 Pharma LLC | OXYCODONE HYDROCHLORIDE 10 mg/5mL; ACETAMINOPHEN 300 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| Forte Bio-Pharma LLC | OXYCODONE HYDROCHLORIDE 10 mg/5mL; ACETAMINOPHEN 300 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| FH2 Pharma LLC | OXYCODONE HYDROCHLORIDE 300 mg/5mL; ACETAMINOPHEN 10 mg/5mL | Jul 22, 2026 | Aug 19, 2026 |
| Forte Bio-Pharma LLC | OXYCODONE HYDROCHLORIDE 300 mg/5mL; ACETAMINOPHEN 10 mg/5mL | Jul 22, 2026 | Aug 19, 2026 |
| FH2 Pharma LLC | ACETAMINOPHEN 300 mg/5mL; OXYCODONE HYDROCHLORIDE 10 mg/5mL | Jul 15, 2026 | Jul 15, 2026 |
| Forte Bio-Pharma LLC | ACETAMINOPHEN 300 mg/5mL; OXYCODONE HYDROCHLORIDE 10 mg/5mL | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "oxycodone hydrochloride and acetaminophen — NDC 72887-0648-12," retrieved September 3, 2026, https://drugdashboards.com/drug/72887064812.
Free to cite with attribution — see how the data is put together.