Folotyn

pralatrexate · PRALATREXATE 40 mg/2mL · Injection · Intravenous · Acrotech Biopharma Inc

NDC 72893-0005-01 · 1 VIAL in 1 CARTON / 2 mL in 1 VIAL · NDA · View full market →

The short version

Just 3 companies supply this market — thin enough that a single exit would be felt immediately. One of its named manufacturing plants, Simtra Deutschland GmbH, failed FDA inspectionwithin the last two years — the agency’s most serious outcome.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built

Data sources

CMS NADAC (pharmacy acquisition, weekly)
CMS Part B ASP quarterly payment limits
CMS Maximum Fair Prices (IRA negotiated, NDC-level)
Medicare Part D Spending by Drug (data.cms.gov, name-matched)
VA FSS / Big4 federal contract prices (va.gov, twice monthly)
ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
California SB-17 WAC filings (list price, per package)

Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Medicare Part B pays (ASP+6%)$386.12per billing unit (1 MG)HCPCS J9307 · Jul 1, 2026
Federal contracts pay (FSS)$10,562.19per package of 2MLAcrotech Biopharma LLC · Jan 1, 2026

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed

$15,568.34

Reported to Texas DSHS · 2026 annual filing · Acrotech Biopharma

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicare Part B (ASP)

Payment limit per 1 MG

$386.122

HCPCS J9307 · Jul 1, 2026 quarter · typically ASP + 6%

Medicaid spend (2025)

$73,859

12 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Where it's made

Simtra Deutschland GmbHOAIGermany
manufacture

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

Part D specialty tier
Costs ≥ $950/fill
Biologic (BLA)
Injectable / infused
Orphan-drug exclusivity
REMS program

Regulatory

Application: NDA022468
TE code: AP
Approval date: Sep 24, 2009
Patents / exclusivity: None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of pralatrexate (Injection)

Labeler	Strength	First seen	Last seen
Acrotech Biopharma Inc	PRALATREXATE 20 mg/mL	Jul 15, 2026	Sep 2, 2026
Acrotech Biopharma Inc	PRALATREXATE 40 mg/2mL	Jul 15, 2026	Sep 2, 2026
Dr.Reddy's Laboratories Inc.,	PRALATREXATE 20 mg/mL	Jul 15, 2026	Sep 2, 2026
Dr.Reddy's Laboratories Inc.,	PRALATREXATE 40 mg/2mL	Jul 15, 2026	Sep 2, 2026
Fresenius Kabi USA, LLC	PRALATREXATE 20 mg/mL	Jul 15, 2026	Sep 2, 2026
Fresenius Kabi USA, LLC	PRALATREXATE 40 mg/2mL	Jul 15, 2026	Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Folotyn — NDC 72893-0005-01," retrieved September 3, 2026, https://drugdashboards.com/drug/72893000501.

Free to cite with attribution — see how the data is put together.