The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
isosorbide dinitrate and hydralazine hydrochloride
isosorbide dinitrate and hydralazine hydrochloride · ISOSORBIDE DINITRATE 20 mg/1; HYDRALAZINE HYDROCHLORIDE 37.5 mg/1 · Tablet, Film Coated · Oral · A2A Integrated Pharmaceuticals
NDC 73141-0012-03 · 90 TABLET, FILM COATED in 1 BOTTLE · ANDA · View full market →
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for isosorbide dinitrate and hydralazine hydrochloride (oral solid) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- I 3 Pharmaceuticals, LlcUnited Statesmanufacture · pack
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Regulatory
- Application
- ANDA215988
- TE code
- AB
- Approval date
- Jan 17, 2024
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of isosorbide dinitrate and hydralazine hydrochloride (Tablet, Film Coated)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| A2A Integrated Pharmaceuticals | ISOSORBIDE DINITRATE 20 mg/1; HYDRALAZINE HYDROCHLORIDE 37.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| i3 Pharmaceuticals, LLC | ISOSORBIDE DINITRATE 20 mg/1; HYDRALAZINE HYDROCHLORIDE 37.5 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| A2A Integrated Pharmaceuticals | ISOSORBIDE DINITRATE 37.5 mg/1; HYDRALAZINE HYDROCHLORIDE 20 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| i3 Pharmaceuticals, LLC | ISOSORBIDE DINITRATE 37.5 mg/1; HYDRALAZINE HYDROCHLORIDE 20 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| A2A Integrated Pharmaceuticals | HYDRALAZINE HYDROCHLORIDE 37.5 mg/1; ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| i3 Pharmaceuticals, LLC | HYDRALAZINE HYDROCHLORIDE 37.5 mg/1; ISOSORBIDE DINITRATE 20 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "isosorbide dinitrate and hydralazine hydrochloride — NDC 73141-0012-03," retrieved September 3, 2026, https://drugdashboards.com/drug/73141001203.
Free to cite with attribution — see how the data is put together.