The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Anti-Diarrheal/Anti-Gas Caplets
Loperamide Hydrochloride 2mg, Simethicone 125mg · LOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1 · Tablet · Oral · Yyba Corp
NDC 73581-0178-24 · 4 BLISTER PACK in 1 CARTON / 6 TABLET in 1 BLISTER PACK · ANDA · View full market →
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Regulatory
- Application
- ANDA213484
- TE code
- —
- Approval date
- Sep 10, 2021
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Loperamide Hydrochloride 2mg, Simethicone 125mg (Tablet)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Wal-Mart Stores, Inc. | LOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Yyba Corp | LOPERAMIDE HYDROCHLORIDE 2 mg/1; DIMETHICONE 125 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Wal-Mart Stores, Inc. | LOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Yyba Corp | LOPERAMIDE HYDROCHLORIDE 125 mg/1; DIMETHICONE 2 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Wal-Mart Stores, Inc. | DIMETHICONE 125 mg/1; LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Yyba Corp | DIMETHICONE 125 mg/1; LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Anti-Diarrheal/Anti-Gas Caplets — NDC 73581-0178-24," retrieved September 3, 2026, https://drugdashboards.com/drug/73581017824.
Free to cite with attribution — see how the data is put together.