DrugDashboards

Buphenyl

sodium phenylbutyrate · SODIUM PHENYLBUTYRATE .94 g/g · Powder · Oral · Horizon Therapeutics USA, Inc.

NDC 75987-0070-09 · 1 BOTTLE in 1 CARTON / 250 g in 1 BOTTLE · NDA · View full market →

The short version

11 companies supply this market — deep enough that no single failure threatens the supply.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Part D plans paid (avg)$37.18per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$50.07per unitnegotiated price across 2 plans — before rebates · Jul 1, 2024

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$50.07per unit
middle half $50.07$50.07 · 2 plans · Jul 1, 2024
Est. net of rebates
$30.04–$37.55
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
of plans cover it

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 3 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed
$13,627.50
Reported to Texas DSHS · 2026 annual filing · Horizon Pharma Usa Inc

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$799,930
43 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $29,995.56 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA020573
TE code
Approval date
Apr 30, 1996
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of sodium phenylbutyrate (Powder)

LabelerStrengthFirst seenLast seen
Apothecon Pharmaceuticals Pvt LtdSODIUM PHENYLBUTYRATE .999 kg/.999kgJul 15, 2026Sep 2, 2026
AX Pharmaceutical CorpSODIUM PHENYLBUTYRATE 1 g/gJul 15, 2026Sep 2, 2026
CU Chemie Uetikon GmbHSODIUM PHENYLBUTYRATE 1 kg/kgJul 15, 2026Sep 2, 2026
Darmerica, LlcSODIUM PHENYLBUTYRATE 1 g/gJul 15, 2026Sep 2, 2026
Horizon Therapeutics USA, Inc.SODIUM PHENYLBUTYRATE .94 g/gJul 15, 2026Sep 2, 2026
Medisca Inc.SODIUM PHENYLBUTYRATE 1 g/gJul 15, 2026Sep 2, 2026
Par Active Technologies Private LimitedSODIUM PHENYLBUTYRATE 5 kg/5kgJul 15, 2026Sep 2, 2026
Par Health USA, LLCSODIUM PHENYLBUTYRATE .94 g/gJul 15, 2026Sep 2, 2026
PcasSODIUM PHENYLBUTYRATE 1 kg/kgJul 15, 2026Sep 2, 2026
Sri Krishna Pharmaceuticals Ltd. Unit ISODIUM PHENYLBUTYRATE 1 kg/kgJul 15, 2026Sep 2, 2026
Sthree Chemicals Private LimitedSODIUM PHENYLBUTYRATE 35 kg/35kgJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Buphenyl — NDC 75987-0070-09," retrieved September 3, 2026, https://drugdashboards.com/drug/75987007009.

Free to cite with attribution — see how the data is put together.