The short version
25 companies supply this market — deep enough that no single failure threatens the supply. The price is up 9% over the past year, to $1.23 per mL. A Class II recall hit this product in the past year (International Medication Systems Ltd.). One of its named manufacturing plants, International Medication Systems, Ltd., failed FDA inspectionwithin the last two years — the agency’s most serious outcome. Put together: worth watching — several of the pressures that precede supply trouble are present at once. Historically, drugs in this position went on to a new shortage within 90 days about 0.5% of the time — roughly 4× the typical drug (0.1%).
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