DrugDashboards

Sodium Bicarbonate

Sodium Bicarbonate · SODIUM BICARBONATE 84 mg/mL · Injection · Intravenous · International Medication Systems, Limited

NDC 76329-3352-01 · 1 SYRINGE in 1 CARTON / 50 mL in 1 SYRINGE · ANDA · View full market →

The short version

6 companies supply this market — a reasonable cushion if one runs into trouble. The price has jumped 121% in a year, to $0.3288 per mL — sharp rises like this often mean supply is already tightening. It is in shortage right now — FDA lists the reason as “demand increase for the drug. One of its named manufacturing plants, International Medication Systems, Ltd., failed FDA inspectionwithin the last two years — the agency’s most serious outcome. Put together: worth watching — several of the pressures that precede supply trouble are present at once.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.3288per MLinvoice-surveyed acquisition cost · Dec 18, 2024
  • Part D plans paid (avg)$0.2496per dosage unitgross, before rebates — matched by drug name · 2024
  • Federal contracts pay (FSS)$117.49per package of 10X50MLAmphastar Pharmaceuticals, Inc. · Jan 15, 2022

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.2$0.4Apr 2015Dec 2024$0.3288
7 price points · per ML · last surveyed Invalid DateSource: CMS NADAC

Medicaid spend (2025)

$92,442
2,181 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

35Elevated risk

The score is counting real pressure here. One of these alone is routine; it’s the combination that makes this market worth watching.

  • in shortage now+25
  • sterile injectable+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.5%chance of a new FDA shortage posting for sodium bicarbonate (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 3× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $66.59 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA203449
TE code
AP
Approval date
Sep 19, 2017
Patents / exclusivity
None on file

Shortage history

  • In shortage now Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 76329-3352-1)Mar 1, 2017
    Demand increase for the drug
    month 115 — 6× the typical 20-month injectable shortage · model puts 15% odds it resolves within 6 months

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Sodium Bicarbonate (Injection)

LabelerStrengthFirst seenLast seen
Emnar Pharma Private LimitedSODIUM BICARBONATE 25 kg/25kgJul 15, 2026Sep 2, 2026
HF Acquisition Co LLC, DBA HealthFirstSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
International Medication Systems, LimitedSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
Medical Purchasing Solutions, LLCSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
ProPharma DistributionSODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026
Remedyrepack Inc.SODIUM BICARBONATE 84 mg/mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Sodium Bicarbonate — NDC 76329-3352-01," retrieved September 3, 2026, https://drugdashboards.com/drug/76329335201.

Free to cite with attribution — see how the data is put together.