DrugDashboards

Antihistamine

Diphenhydramine HCl · DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1 · Capsule · Oral · Gendose Pharmaceuticals, LLC

NDC 77333-0227-10 · 100 BLISTER PACK in 1 BOX / 1 CAPSULE in 1 BLISTER PACK · OTC MONOGRAPH DRUG · View full market →

The short version

32 companies supply this market — deep enough that no single failure threatens the supply.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for diphenhydramine hcl (oral solid) in the next 90 days

sole-source market · price up 4% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
M012
TE code
—
Approval date
—
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Diphenhydramine HCl (Capsule)

LabelerStrengthFirst seenLast seen
Harris Teeter, LLCDIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 3, 2026
NuCare Pharmaceuticals, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 3, 2026
QUALITY CHOICE (Chain Drug Marketing Association)DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 3, 2026
Safeway, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 3, 2026
Aarna Usa Inc.DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Aarna Usa Inc.DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Akron Pharma Inc.DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Akron Pharma Inc.DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Amerisource BergenDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Army And Air Force Exchange ServiceDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Bi-MartDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Cardinal Health (Leader) 70000DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Cardinal Health 107, LLCDIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Chattem, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
CVS PharmacyDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
CVS Pharmacy, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Dolgencorp, LlcDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC)DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Family Dollar (FAMILY WELLNESS)DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
FSA Store Inc. (Caring Mills)DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Geiss, Destin & Dunn Inc.DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Gendose Pharmaceuticals, LLCDIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Gendose Pharmaceuticals, LLCDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Good Sense (Geiss, Destin & Dunn, Inc.)DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
H E BDIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsDIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals,Inc.DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
PD-Rx Pharmaceuticals, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
PD-Rx Pharmaceuticals, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Pharbest Pharmaceuticals, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Pharbest Pharmaceuticals, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals Inc.DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Proficient Rx LPDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Proficient Rx LPDIPHENHYDRAMINE HYDROCHLORIDE 50 mg/1Jul 15, 2026Sep 2, 2026
Reliable 1 Laboratories LLCDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026
Rite Aid CorporationDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Antihistamine — NDC 77333-0227-10," retrieved September 3, 2026, https://drugdashboards.com/drug/77333022710.

Free to cite with attribution — see how the data is put together.