The short version
12 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Sulfamethoxazole and Trimethoprim
Sulfamethoxazole and Trimethoprim · SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL · Suspension · Oral · Kesin Pharma
NDC 81033-0012-40 · 40 CUP, UNIT-DOSE in 1 CARTON / 20 mL in 1 CUP, UNIT-DOSE · ANDA · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 65862-0496-47) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$0.0850per unit
middle half $0.0727–$0.1037 · 5,470 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $0.0850
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 3 · prior auth 0% · step therapy 0% · qty limit 0%
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Estimated fill cost
WAC per package, as filed
$550.00
Reported to Texas DSHS · 2026 annual filing · Kesin Pharma Corporation
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for sulfamethoxazole and trimethoprim (other) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- Kesin Pharma CorporationUnited Stateslabel · pack · repack
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Regulatory
- Application
- ANDA077612
- TE code
- AB
- Approval date
- Nov 13, 2006
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Sulfamethoxazole and Trimethoprim (Suspension)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| PAI Holdings, LLC dba PAI Pharma | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Sep 3, 2026 |
| American Health Packaging | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| ANI Pharmaceuticals, Inc. | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Atlantic Biologicals Corp. | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Chartwell Governmental & Specialty RX, LLC. | SULFAMETHOXAZOLE 800 mg/20mL; TRIMETHOPRIM 160 mg/20mL | Jul 15, 2026 | Sep 2, 2026 |
| Chartwell RX, LLC | SULFAMETHOXAZOLE 800 mg/20mL; TRIMETHOPRIM 160 mg/20mL | Jul 15, 2026 | Sep 2, 2026 |
| Chartwell RX, LLC | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Kesin Pharma | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Prasco Laboratories | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals Inc. | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals, Inc. | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Sep 2, 2026 |
| A-S Medication Solutions | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Aug 31, 2026 |
| RedPharm Drug, Inc. | SULFAMETHOXAZOLE 200 mg/5mL; TRIMETHOPRIM 40 mg/5mL | Jul 15, 2026 | Jul 29, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Sulfamethoxazole and Trimethoprim — NDC 81033-0012-40," retrieved September 3, 2026, https://drugdashboards.com/drug/81033001240.
Free to cite with attribution — see how the data is put together.