The short version
Only one company currently supplies this market — there is no backup if it stumbles.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Balance Plus Cream
estriol,estradiol,progesterone,dhea · PROGESTERONE 6000 mg/102g; ESTRIOL 240 mg/102g; ESTRADIOL 60 mg/102g; PRASTERONE 1000 mg/102g · Cream · Transdermal · SHYNE BRANDS/BIOLabs PRO
NDC 82018-0028-04 · 102 g in 1 BOTTLE, PUMP · UNAPPROVED DRUG OTHER · View full market →
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
Regulatory
- Application
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- TE code
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- Approval date
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- Patents / exclusivity
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Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of estriol,estradiol,progesterone,dhea (Cream)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| SHYNE BRANDS/BIOLabs PRO | PROGESTERONE 6000 mg/102g; ESTRIOL 240 mg/102g; ESTRADIOL 60 mg/102g; PRASTERONE 1000 mg/102g | Aug 26, 2026 | Sep 2, 2026 |
| SHYNE BRANDS/BIOLabs PRO | PROGESTERONE 60 mg/102g; ESTRIOL 240 mg/102g; ESTRADIOL 1000 mg/102g; PRASTERONE 6000 mg/102g | Jul 22, 2026 | Aug 19, 2026 |
| SHYNE BRANDS/BIOLabs PRO | ESTRADIOL 60 mg/102g; ESTRIOL 240 mg/102g; PRASTERONE 1000 mg/102g; PROGESTERONE 6000 mg/102g | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Balance Plus Cream — NDC 82018-0028-04," retrieved September 3, 2026, https://drugdashboards.com/drug/82018002804.
Free to cite with attribution — see how the data is put together.