DrugDashboards

Brimonidine tartrate

brimonidine tartrate · BRIMONIDINE TARTRATE 1 mg/mL · Solution/ Drops · Ophthalmic · Pacific Pharma, Inc.

NDC 82182-0321-05 · 1 BOTTLE, DROPPER in 1 CARTON / 5 mL in 1 BOTTLE, DROPPER · NDA AUTHORIZED GENERIC · View full market →

The short version

14 companies supply this market — deep enough that no single failure threatens the supply. The generic price has fallen 35% in a year, to $10.17 per mL — and generics that get this cheap tend to get abandoned rather than defended. The brand (Alphagan P) runs $37.33 per mL 3.7× more. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$10.17per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D plans paid (avg)$3.90per dosage unitgross, before rebates — matched by drug name · 2024
  • Medicaid generic ceiling (FUL)$63.31per MLweighted avg manufacturer price $36.1761 · Mar 1, 2024623% of what pharmacies pay — higher than 95% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00023-9321-05) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$39.49per unit
middle half $36.34$39.81 · 1,403 plans · Apr 1, 2026
Est. net of rebates
≈ $39.49
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
26%of plans cover it
tier 3 · prior auth 0% · step therapy 0% · qty limit 1%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$20.00$40.00Feb 2024Sep 2026$10.17
32 price points · per MLSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$80.68
Reported to Texas DSHS · 2026 annual filing · Zydus Pharmaceuticals (USA) Inc

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$91,633
587 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

8Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • price down 33% year over year+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.2%chance of a new FDA shortage posting for brimonidine tartrate (other) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA021770
TE code
AB
Approval date
Aug 19, 2005
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of brimonidine tartrate (Solution/ Drops)

LabelerStrengthFirst seenLast seen
Bausch & Lomb IncorporatedBRIMONIDINE TARTRATE .25 mg/mLJul 15, 2026Sep 3, 2026
Alembic Pharmaceuticals Inc.BRIMONIDINE TARTRATE 1 mg/mLJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedBRIMONIDINE TARTRATE 1 mg/mLJul 15, 2026Sep 2, 2026
Allergan, Inc.BRIMONIDINE TARTRATE 1.5 mg/mLJul 15, 2026Sep 2, 2026
Allergan, Inc.BRIMONIDINE TARTRATE 1 mg/mLJul 15, 2026Sep 2, 2026
Apotex Corp.BRIMONIDINE TARTRATE 1.5 mg/mLJul 15, 2026Sep 2, 2026
Apotex Corp.BRIMONIDINE TARTRATE 1 mg/mLJul 15, 2026Sep 2, 2026
Bausch & Lomb IncorporatedBRIMONIDINE TARTRATE 2 mg/mLJul 15, 2026Sep 2, 2026
Dr Reddy's Laboratories Inc.BRIMONIDINE TARTRATE .25 mg/mLJul 15, 2026Sep 2, 2026
Florida Pharmaceutical Products, LLCBRIMONIDINE TARTRATE 2 mg/mgJul 15, 2026Sep 2, 2026
Gland Pharma LimitedBRIMONIDINE TARTRATE 1 mg/mLJul 15, 2026Sep 2, 2026
Indoco Remedies LimitedBRIMONIDINE TARTRATE 2 mg/mgJul 15, 2026Sep 2, 2026
Laboratoire UnitherBRIMONIDINE TARTRATE .25 mg/mLJul 15, 2026Sep 2, 2026
Micro Labs LimitedBRIMONIDINE TARTRATE 2 mg/mLJul 15, 2026Sep 2, 2026
Micro Labs LimitedBRIMONIDINE TARTRATE 1 mg/mLJul 15, 2026Sep 2, 2026
Pacific Pharma, Inc.BRIMONIDINE TARTRATE 1.5 mg/mLJul 15, 2026Sep 2, 2026
Pacific Pharma, Inc.BRIMONIDINE TARTRATE 1 mg/mLJul 15, 2026Sep 2, 2026
Sandoz IncBRIMONIDINE TARTRATE 1 mg/mLJul 15, 2026Sep 2, 2026
Somerset Therapeutics, LLCBRIMONIDINE TARTRATE 2 mg/mLJul 15, 2026Aug 31, 2026
Somerset Therapeutics, LLCBRIMONIDINE TARTRATE 1 mg/mLJul 15, 2026Aug 31, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Brimonidine tartrate — NDC 82182-0321-05," retrieved September 3, 2026, https://drugdashboards.com/drug/82182032105.

Free to cite with attribution — see how the data is put together.