The short version
Just 3 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Freskaro Calamine Plus
zinc oxide lotion · ZINC OXIDE 80 mg/mL; PRAMOXINE HYDROCHLORIDE 10 mg/mL · Lotion · Topical · Pharma Nobis, LLC
NDC 82645-0420-96 · 177 mL in 1 BOTTLE, PLASTIC · OTC MONOGRAPH DRUG · View full market →
Medicare Part D
Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for zinc oxide lotion (other) in the next 90 days
sole-source market · price up 5% YoY
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Regulatory
- Application
- M016
- TE code
- —
- Approval date
- —
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of zinc oxide lotion (Lotion)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Cardinal Health, 110 dba Leader | ZINC OXIDE 80 mg/mL; PRAMOXINE HYDROCHLORIDE 10 mg/mL | Aug 26, 2026 | Sep 2, 2026 |
| Innisfree Corporation | ZINC OXIDE 8 g/50mL | Jul 15, 2026 | Sep 2, 2026 |
| Pharma Nobis, LLC | ZINC OXIDE 80 mg/mL; PRAMOXINE HYDROCHLORIDE 10 mg/mL | Aug 26, 2026 | Sep 2, 2026 |
| Cardinal Health, 110 dba Leader | ZINC OXIDE 10 mg/mL; PRAMOXINE HYDROCHLORIDE 80 mg/mL | Jul 22, 2026 | Aug 19, 2026 |
| Pharma Nobis, LLC | ZINC OXIDE 10 mg/mL; PRAMOXINE HYDROCHLORIDE 80 mg/mL | Jul 22, 2026 | Aug 19, 2026 |
| Cardinal Health, 110 dba Leader | PRAMOXINE HYDROCHLORIDE 10 mg/mL; ZINC OXIDE 80 mg/mL | Jul 15, 2026 | Jul 15, 2026 |
| Pharma Nobis, LLC | PRAMOXINE HYDROCHLORIDE 10 mg/mL; ZINC OXIDE 80 mg/mL | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Freskaro Calamine Plus — NDC 82645-0420-96," retrieved September 3, 2026, https://drugdashboards.com/drug/82645042096.
Free to cite with attribution — see how the data is put together.