DrugDashboards

ValuMeds Extra Strength Headache Relief

Acetaminophen, Aspirin, Caffeine · ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1 · Tablet · Oral · Cabinet Health P.B.C.

NDC 82725-1023-01 · 300 TABLET in 1 BOTTLE · OTC MONOGRAPH DRUG · View full market →

The short version

25 companies supply this market — deep enough that no single failure threatens the supply.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for acetaminophen, aspirin, caffeine (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
M013
TE code
Approval date
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Acetaminophen, Aspirin, Caffeine (Tablet)

LabelerStrengthFirst seenLast seen
HyVee IncACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Sep 3, 2026Sep 3, 2026
Opmx LlcACETAMINOPHEN 250 mg/1; CAFFEINE 65 mg/1; ASPIRIN 250 mg/1Aug 26, 2026Sep 3, 2026
Opmx LlcCAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1Aug 26, 2026Sep 3, 2026
WalgreensACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 3, 2026
WalgreensACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 3, 2026
Belmora LLCACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
Better Living Brands, LlcASPIRIN 250 mg/1; ACETAMINOPHEN 250 mg/1; CAFFEINE 65 mg/1Jul 22, 2026Sep 2, 2026
Bioventure Healthcare - FZEACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
Cabinet Health P.B.C.ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
CVS PharmacyACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC)ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
H E BACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
Hi-Tech Nutaceuticals, LLCCAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1Aug 26, 2026Sep 2, 2026
Lil' Drug Store Products, Inc.ACETAMINOPHEN 250 mg/1; CAFFEINE 65 mg/1; ASPIRIN 250 mg/1Aug 26, 2026Sep 2, 2026
Magno-Humphries, Inc.ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
Nuvicare LlcCAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1Aug 26, 2026Sep 2, 2026
Opmx LlcASPIRIN 250 mg/1; CAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1Aug 26, 2026Sep 2, 2026
P & L Development, LLCACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
Pharmadel LLCACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
Safeway, Inc.ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
Strive Pharmaceuticals Inc.ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
TARGET CorporationACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Sep 2, 2026
WalgreensASPIRIN 250 mg/1; CAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1Aug 26, 2026Sep 2, 2026
Walmart Inc.ACETAMINOPHEN 250 mg/1; CAFFEINE 65 mg/1; ASPIRIN 250 mg/1Aug 26, 2026Sep 2, 2026
Family Dollar (FAMILY WELLNESS)ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Aug 28, 2026
Pioneer Life Sciences, LLCCAFFEINE 65 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1Aug 26, 2026Aug 28, 2026
The Kroger Co.ACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Aug 28, 2026
Opmx LlcACETAMINOPHEN 250 mg/1; CAFFEINE 250 mg/1; ASPIRIN 65 mg/1Jul 22, 2026Aug 21, 2026
Pioneer Life Sciences, LLCCAFFEINE 250 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 65 mg/1Jul 22, 2026Aug 21, 2026
Opmx LlcCAFFEINE 250 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 65 mg/1Jul 22, 2026Aug 20, 2026
Hi-Tech Nutaceuticals, LLCCAFFEINE 250 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 65 mg/1Jul 22, 2026Aug 19, 2026
Lil' Drug Store Products, Inc.ACETAMINOPHEN 250 mg/1; CAFFEINE 250 mg/1; ASPIRIN 65 mg/1Jul 22, 2026Aug 19, 2026
Nuvicare LlcCAFFEINE 250 mg/1; ACETAMINOPHEN 250 mg/1; ASPIRIN 65 mg/1Jul 22, 2026Aug 19, 2026
Opmx LlcASPIRIN 250 mg/1; CAFFEINE 250 mg/1; ACETAMINOPHEN 65 mg/1Jul 22, 2026Aug 19, 2026
WalgreensASPIRIN 250 mg/1; CAFFEINE 250 mg/1; ACETAMINOPHEN 65 mg/1Jul 22, 2026Aug 19, 2026
Walmart Inc.ACETAMINOPHEN 250 mg/1; CAFFEINE 250 mg/1; ASPIRIN 65 mg/1Jul 22, 2026Aug 19, 2026
Pioneer Life Sciences, LLCACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Jul 19, 2026
Opmx LlcACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Jul 16, 2026
Better Living Brands, LlcACETAMINOPHEN 250 mg/1; ASPIRIN 250 mg/1; CAFFEINE 65 mg/1Jul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "ValuMeds Extra Strength Headache Relief — NDC 82725-1023-01," retrieved September 3, 2026, https://drugdashboards.com/drug/82725102301.

Free to cite with attribution — see how the data is put together.