The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Analpram HC
hydrocortisone acetate and pramoxine hydrochloride · HYDROCORTISONE ACETATE 25 mg/mL; PRAMOXINE HYDROCHLORIDE 10 mg/mL · Lotion · Topical · Legacy Pharma USA Inc.
NDC 83107-0020-02 · 59 mL in 1 BOTTLE, PLASTIC · ANDA · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 83107-0021-04) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$3.42per unit
middle half $3.41–$3.45 · 21 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $3.42
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
0%of plans cover it
tier 4 · prior auth 0% · step therapy 0% · qty limit 0%
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 3 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Estimated fill cost
WAC per package, as filed
$337.79
Reported to Texas DSHS · 2026 annual filing · Legacy Pharma USA, Inc.
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for hydrocortisone acetate and pramoxine hydrochloride (other) in the next 90 days
sole-source market · price up 5% YoY
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Regulatory
- Application
- ANDA085979
- TE code
- —
- Approval date
- Jan 1, 1982
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of hydrocortisone acetate and pramoxine hydrochloride (Lotion)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Legacy Pharma USA Inc. | HYDROCORTISONE ACETATE 25 mg/mL; PRAMOXINE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Sep 3, 2026 |
| Legacy Pharma USA Inc. | HYDROCORTISONE ACETATE 10 mg/mL; PRAMOXINE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Sebela Pharmaceuticals Inc. | HYDROCORTISONE ACETATE 10 mg/mL; PRAMOXINE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Sebela Pharmaceuticals Inc. | HYDROCORTISONE ACETATE 25 mg/mL; PRAMOXINE HYDROCHLORIDE 10 mg/mL | Jul 15, 2026 | Aug 28, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Analpram HC — NDC 83107-0020-02," retrieved September 3, 2026, https://drugdashboards.com/drug/83107002002.
Free to cite with attribution — see how the data is put together.