The short version
Just 2 companies supply this market — thin enough that a single exit would be felt immediately.
Market view
midazolam hydrochloride · Powder
2 marketed package NDCs · 2 active manufacturers
Most dispensed: 5 mg/mL · Injection, Solution · #10 vial, multi-doses/carton / 10 ml in 1 vial, multi-dose · 5 mg/mL · Injection, Solution · #10 vial, single-doses/carton / 1 ml in 1 vial, single-dose · 5 mg/mL · Injection, Solution · #10 vial, single-doses/carton / 2 ml in 1 vial, single-dose · 1 mg/mL · Injection, Solution · #25 vial, single-doses/carton / 2 ml in 1 vial, single-dose
What changed in the last 90 days
Every detected change for midazolam hydrochloride, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- MidazolamAug 19, 2026Price upNADAC $0.23391 → $0.23431 per unit (+0.17%)
- Midazolam hydrochlorideAug 19, 2026Price downNADAC $0.45002 → $0.38167 per unit (-15.19%)
- Midazolam hydrochlorideAug 19, 2026Price upNADAC $0.23391 → $0.23431 per unit (+0.17%)
- Midazolam HydrochlorideAug 19, 2026Price downNADAC $0.66512 → $0.63601 per unit (-4.38%)
- MidazolamAug 19, 2026Price downNADAC $0.45002 → $0.38167 per unit (-15.19%)
- MidazolamAug 19, 2026Price downNADAC $0.56853 → $0.56714 per unit (-0.24%)
- MidazolamAug 19, 2026Price upNADAC $1.19978 → $1.22143 per unit (+1.8%)
- MidazolamAug 19, 2026Price downNADAC $0.56853 → $0.56714 per unit (-0.24%)
- MidazolamAug 19, 2026Price upNADAC $1.19978 → $1.22143 per unit (+1.8%)
- Midazolam HydrochlorideAug 19, 2026Price downNADAC $0.66512 → $0.63601 per unit (-4.38%)
Same drug class
Other molecules FDA puts in Benzodiazepine, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- flurazepam hydrochloride· in shortage
- midazolam· in shortage
- clonazepam· in shortage
- lorazepam· in shortage
- alprazolam c-iv· 1 maker
- alprazolam odt c-iv· 1 maker
- chlordiazepoxide hydrochloride, clidinium bromide· 1 maker
- diazepam intensol· 1 maker
- diazepam oral solution (concentrate)· 1 maker
- midazolam in 0.8% sodium chloride· 1 maker
- midazolam injection, 10 mg· 1 maker
- temazepam civ· 1 maker
Common questions
- Is Midazolam hydrochloride in shortage right now?
- Yes. FDA currently lists Midazolam hydrochloride in shortage. This page is rebuilt every morning from FDA's shortage database.
- Who makes Midazolam hydrochloride?
- 21 companies have marketed Midazolam hydrochloride in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Midazolam hydrochloride cost?
- The typical pharmacy pays about $0.5671 per mL, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.