The short version
20 companies supply this market — deep enough that no single failure threatens the supply. The generic price is down 14% over the past year, to $0.2553 per unit. The brand runs $8.85 per unit — 35× more.
Market view
desloratadine
37 marketed package NDCs · 20 active manufacturers
Most dispensed: 5 mg · Tablet, Film Coated · #100 tablet, film coateds/bottle · 5 mg · Tablet · #100 tablets/bottle, plastic · 5 mg · Tablet · #500 tablets/bottle, plastic · 5 mg · Tablet, Film Coated · #500 tablet, film coateds/bottle
Price range and competition
RSS: changes for this drugpriced separately — they are not the same market
Generic products only. Every company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Sep 2026 — typical price $0.2553 · middle half $0.2553–$1.39 · full range $0.2553–$4.79 · 8 products · 20 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for desloratadine, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- DesloratadineAug 28, 2026Mfr enteredMorepen Bio Inc. · desloratadine
- DesloratadineAug 28, 2026New productMorepen Bio Inc.
- DesloratadineAug 28, 2026New productMorepen Bio Inc.
- DesloratadineAug 19, 2026Price downNADAC $0.26149 → $0.25526 per unit (-2.38%)
- DesloratadineAug 19, 2026Price downNADAC $0.26149 → $0.25526 per unit (-2.38%)
- DesloratadineAug 19, 2026Price downNADAC $0.26149 → $0.25526 per unit (-2.38%)
- DesloratadineAug 19, 2026Price downNADAC $0.26149 → $0.25526 per unit (-2.38%)
- DesloratadineAug 19, 2026Price downNADAC $0.26149 → $0.25526 per unit (-2.38%)
- DesloratadineAug 19, 2026Price downNADAC $0.26149 → $0.25526 per unit (-2.38%)
- DesloratadineAug 19, 2026Price upNADAC $4.7821 → $4.78821 per unit (+0.13%)
Same drug class
Other molecules FDA puts in Histamine-1 Receptor Antagonist, with whether each is in shortage right now. Same class is not the same drug — substitution is a clinical decision, and this is a supply picture, not a recommendation.
- 430r walgreens acetaminophen 500 mg,diphenhydramine hcl 25 mg tablet· 1 maker
- acetaminophen , diphenhydramine hcl,phenylephrine hcl· 1 maker
- acetaminophen , diphenhydramine hydrochloride,phenylephrine hydrochloride· 1 maker
- acetaminophen 325 mg, diphenhydramine hcl 12.5 mg, phenylephrine hcl 5 mg· 1 maker
- acetaminophen 500 mg and diphenhydramine hcl 25 mg· 1 maker
- acetaminophen 500 mg,diphenhydramine hydrochloride 25 mg tablet· 1 maker
- acetaminophen 500mg / diphenhydramine hcl 25mg· 1 maker
- acetaminophen 500mg/ diphenhydramine hcl 25mg· 1 maker
- acetaminophen chlorpheniramine maleate dextromethorphan hydrobromide phenylepherine hydrochloride· 1 maker
- acetaminophen phenylephrine hcl chlorpheniramine maleate· 1 maker
- acetaminophen-chlorpheniramine maleate-dextromethorphan hbr-guaifenesin-phenylephrine hcl· 1 maker
- acetaminophen-dextromethorphan hbr-phenylephrine hcl-chlorpheniramine maleate· 1 maker
Common questions
- Is Desloratadine in shortage right now?
- No. FDA does not currently list Desloratadine in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Desloratadine?
- 20 companies have marketed Desloratadine in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Desloratadine cost?
- The typical pharmacy pays about $0.2553 per unit, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.