The short version
9 companies supply this market — a reasonable cushion if one runs into trouble. The generic price is down 14% over the past year, to $8.92 per mL. The brand runs $42.25 per mL — 4.7× more.
Market view
difluprednate
11 marketed package NDCs · 9 active manufacturers
Most dispensed: .5 mg/mL · Emulsion · #1 bottle/carton / 5 ml in 1 bottle
Price range and competition
RSS: changes for this drugpriced separately — they are not the same market
Generic products only. Every company selling this drug reports its own price. The line follows the middle of the pack; the shaded band holds the middle half of companies — the wider it is, the more they disagree.
Latest · Sep 2026 — typical price $8.92 · middle half $8.92–$8.92 · full range $8.92–$8.92 · 4 products · 9 companies
ⓘ How this was built
Data sources
- CMS NADAC weekly survey + monthly archives back to 2013 (data.medicaid.gov)
- CMS Federal Upper Limit files (weighted AMP)
- FDA NDC Directory (openFDA) — maker roster
Method
Each month's band spans the NADAC unit prices of every NDC of this drug (min, quartiles, median, max), split into brand and generic cohorts by FDA marketing category. Maker counts come from distinct labelers with the NDC actively listed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
What changed in the last 90 days
Every detected change for difluprednate, newest first — price moves, shortages, recalls, and manufacturers entering or leaving. Detected by comparing each day’s federal data against the day before.
- DifluprednateAug 19, 2026Price upNADAC $7.40566 → $8.91843 per unit (+20.43%)
- DurezolAug 19, 2026Price downNADAC $42.29589 → $42.24913 per unit (-0.11%)
- DifluprednateAug 19, 2026Price upNADAC $7.40566 → $8.91843 per unit (+20.43%)
- DifluprednateAug 19, 2026Price upNADAC $7.40566 → $8.91843 per unit (+20.43%)
- DifluprednateAug 19, 2026Price upNADAC $7.40566 → $8.91843 per unit (+20.43%)
- DifluprednateJul 22, 2026Price upNADAC $7.04791 → $7.40566 per unit (+5.08%)
- DifluprednateJul 22, 2026Price upNADAC $7.04791 → $7.40566 per unit (+5.08%)
- DifluprednateJul 22, 2026Price upNADAC $7.04791 → $7.40566 per unit (+5.08%)
- DurezolJul 22, 2026Price downNADAC $42.32067 → $42.29589 per unit (-0.06%)
- DifluprednateJul 22, 2026Price upNADAC $7.04791 → $7.40566 per unit (+5.08%)
Common questions
- Is Difluprednate in shortage right now?
- No. FDA does not currently list Difluprednate in shortage. This page is rebuilt every morning from FDA's shortage database, so a new posting appears here the day it is published.
- Who makes Difluprednate?
- 9 companies have marketed Difluprednate in the last 30 days, according to the FDA NDC Directory. Every manufacturer and package is listed on this page.
- What does Difluprednate cost?
- The typical pharmacy pays about $8.92 per mL, based on the most recent CMS NADAC survey of actual acquisition costs. That is what the pharmacy pays for the drug itself — not the cash price, and not what an insurer is billed.
All marketed products
Expand a strength to see its dosage forms, then package sizes, then each manufacturer and NDC. Click an NDC for its full detail page.