What changed
Every change our daily ingest detects in the US drug market — 53,165 in the last 30 days. Filter by kind, or subscribe to exactly this view.
ⓘ How this was built
- FDA drug shortages, NDC Directory, drug enforcement (openFDA)
- NADAC prices (data.medicaid.gov)
A diff engine, not a table: each daily run snapshots key fields per NDC, compares against the previous run, and records what moved. The feed below is those records, newest first.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
- SohonosSep 3, 2026New shortageby this manufacturerIpsen Biopharmaceuticals, Inc.'s Sohonos (Capsule, 2.5 mg) is newly in shortage3 companies market sohonos
- metoprolol succinateSep 3, 2026New shortageby this manufacturerTeva Pharmaceuticals USA, Inc.'s metoprolol succinate (Tablet, Extended Release, 100 mg) is newly in shortage65 companies market metoprolol succinate
- metoprolol succinateSep 3, 2026New shortageby this manufacturerTeva Pharmaceuticals USA, Inc.'s metoprolol succinate (Tablet, Extended Release, 25 mg) is newly in shortage65 companies market metoprolol succinate
- Insulin Lispro Junior KwikPenSep 3, 2026New shortageby this manufacturerEli Lilly and Co.'s Insulin Lispro Junior KwikPen (Injection, 100 [iU]/1 mL) is newly in shortage7 companies market insulin lispro junior kwikpen
- ProveraSep 3, 2026New shortageby this manufacturerPfizer Inc.'s Provera (Tablet, 10 mg) is newly in shortage35 companies market provera
- RavictiSep 3, 2026New shortageby this manufacturerAmgen Inc.'s Ravicti (Oral Liquid, 1.1 g/1 mL) is newly in shortage15 companies market ravicti
- metoprolol succinateSep 3, 2026New shortageby this manufacturerTeva Pharmaceuticals USA, Inc.'s metoprolol succinate (Tablet, Extended Release, 50 mg) is newly in shortage65 companies market metoprolol succinate
- MarcaineSep 3, 2026New shortageby this manufacturerHospira, Inc., a Pfizer Company's Marcaine (Injection, 250 mg/50 mL) is newly in shortage35 companies market marcaine · 8 have products in shortage
- RavictiSep 3, 2026New shortageby this manufacturerAmgen Inc.'s Ravicti (Oral Liquid, 1.1 g/1 mL) is newly in shortage15 companies market ravicti
- metoprolol succinateSep 3, 2026New shortageby this manufacturerTeva Pharmaceuticals USA, Inc.'s metoprolol succinate (Tablet, Extended Release, 25 mg) is newly in shortage65 companies market metoprolol succinate
Biggest pharmacy price moves, past 12 months
What pharmacies actually pay (CMS NADAC, surveyed from pharmacy invoices, refreshed weekly) — the drugs where that number moved the most over the past year. Click a drug for its price history and the likely drivers.
ⓘ How this was built
- NADAC — National Average Drug Acquisition Cost (CMS, data.medicaid.gov), weekly
- FDA NDC Directory (openFDA) for product names
Prices are CMS's pharmacy-invoice-surveyed NADAC per unit: weekly from 2025, monthly averages from CMS's per-year archives back to 2013 before that. 12-month movers compare each NDC's latest price to the price in effect a year earlier — the last published price at or before that date, since NADAC only publishes a row when a price changes. Direct arithmetic, no modeling, recomputed at each morning's ingest; drugs with no price update in 6 months are treated as no longer surveyed.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Biggest increases, 12 months
NADAC — what pharmacies pay per unit$0.1033 (Jan 22, 2025) → $1.73 (Jun 17, 2026) per EA
- American Health Packaging left this market around Jul 29, 2026 — fewer manufacturers means less price competition.
Top 2 shown — click a drug to chart it.
Biggest decreases, 12 months
NADAC — what pharmacies pay per unit$11.59 (Aug 20, 2025) → $0.1845 (Jun 3, 2026) per EA
- Cardinal Health 107, LLC left this market around Jul 29, 2026 — fewer manufacturers means less price competition.
Top 8 shown — click a drug to chart it.