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What changed

Every change our daily ingest detects in the US drug market — 53,165 in the last 30 days. Filter by kind, or subscribe to exactly this view.

ⓘ How this was built
Data sources
  • FDA drug shortages, NDC Directory, drug enforcement (openFDA)
  • NADAC prices (data.medicaid.gov)
Method

A diff engine, not a table: each daily run snapshots key fields per NDC, compares against the previous run, and records what moved. The feed below is those records, newest first.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Sep 3, 2026 on the US drug market19 new shortages138 manufacturer exits240 manufacturer entries627 new productsevery change →
All 53,165Price change 28,934Mfr entered 10,505Mfr exited 9,925New product 3,179Product update 310Shortage update 175New recall 67New shortage 59Resolved 6Recall update 3Plant inspection 2RSS for this view

Prices are NADAC per unit (pharmacy acquisition). Sorted by size of move, largest first — showing the top 150 of 28,934 in the window.

Biggest pharmacy price moves, past 12 months

What pharmacies actually pay (CMS NADAC, surveyed from pharmacy invoices, refreshed weekly) — the drugs where that number moved the most over the past year. Click a drug for its price history and the likely drivers.

ⓘ How this was built
Data sources
  • NADAC — National Average Drug Acquisition Cost (CMS, data.medicaid.gov), weekly
  • FDA NDC Directory (openFDA) for product names
Method

Prices are CMS's pharmacy-invoice-surveyed NADAC per unit: weekly from 2025, monthly averages from CMS's per-year archives back to 2013 before that. 12-month movers compare each NDC's latest price to the price in effect a year earlier — the last published price at or before that date, since NADAC only publishes a row when a price changes. Direct arithmetic, no modeling, recomputed at each morning's ingest; drugs with no price update in 6 months are treated as no longer surveyed.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Biggest increases, 12 months

NADAC — what pharmacies pay per unit
+1577%Isoniazid

$0.1033 (Jan 22, 2025) → $1.73 (Jun 17, 2026) per EA

$0$1.00$2.00Nov 2013Sep 2026$1.73
28 price points · per EA · held since Jun 17, 2026Source: CMS NADAC
  • American Health Packaging left this market around Jul 29, 2026 — fewer manufacturers means less price competition.

Top 2 shown — click a drug to chart it.

Biggest decreases, 12 months

NADAC — what pharmacies pay per unit
-98%Dapagliflozin

$11.59 (Aug 20, 2025) → $0.1845 (Jun 3, 2026) per EA

$0$5.00$10.00$15.00Apr 2024Sep 2026$0.1845
28 price points · per EA · held since Jun 3, 2026Source: CMS NADAC
  • Cardinal Health 107, LLC left this market around Jul 29, 2026 — fewer manufacturers means less price competition.

Top 8 shown — click a drug to chart it.