DrugDashboards

Butalbital, Acetaminophen, Caffeine and Codeine Phosphate

Butalbital, Acetaminophen, Caffeine and Codeine Phosphate · BUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 · Capsule · Oral · Hikma Pharmaceuticals USA Inc.

NDC 00054-0650-25 · 100 CAPSULE in 1 BOTTLE · ANDA · View full market →

The short version

Just 3 companies supply this market — thin enough that a single exit would be felt immediately. The price has held steady around $5.31 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$5.31per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Federal contracts pay (FSS)$5.12per unitGolden State Medical Supply, Inc. · Jun 15, 202396% of what pharmacies pay — a deeper discount than 48% of drugs with this benchmark
  • Medicaid generic ceiling (FUL)$6.72per CAPweighted avg manufacturer price $3.8398 · Oct 1, 2025126% of what pharmacies pay — higher than 71% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$2.00$4.00$6.00Mar 2023Sep 2026$5.31
31 price points · per EASource: CMS NADAC

Estimated fill cost

#30 count
$159.41
#90 count
$478.23

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$63,267
304 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

10Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • 3 active manufacturers+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for butalbital, acetaminophen, caffeine and codeine phosphate (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
ANDA215138
TE code
AB
Approval date
Jan 26, 2022
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Butalbital, Acetaminophen, Caffeine and Codeine Phosphate (Capsule)

LabelerStrengthFirst seenLast seen
Bryant Ranch PrepackBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Aug 26, 2026Sep 3, 2026
Breckenridge Pharmaceutical, Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Aug 26, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Aug 26, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Aug 26, 2026Sep 2, 2026
Bryant Ranch PrepackBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 22, 2026Aug 22, 2026
Breckenridge Pharmaceutical, Inc.BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 22, 2026Aug 19, 2026
Hikma Pharmaceuticals USA Inc.BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 22, 2026Aug 19, 2026
Hikma Pharmaceuticals USA Inc.BUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 22, 2026Aug 19, 2026
Bryant Ranch PrepackACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Jul 19, 2026
Breckenridge Pharmaceutical, Inc.ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Jul 15, 2026
Hikma Pharmaceuticals USA Inc.ACETAMINOPHEN 300 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Jul 15, 2026
Hikma Pharmaceuticals USA Inc.ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1Jul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Butalbital, Acetaminophen, Caffeine and Codeine Phosphate — NDC 00054-0650-25," retrieved September 3, 2026, https://drugdashboards.com/drug/00054065025.

Free to cite with attribution — see how the data is put together.