The short version
Just 3 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Butalbital, Acetaminophen, Caffeine and Codeine Phosphate
Butalbital, Acetaminophen, Caffeine and Codeine Phosphate · BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 · Capsule · Oral · Bryant Ranch Prepack
NDC 71335-0194-01 · 20 CAPSULE in 1 BOTTLE · ANDA · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 51991-0073-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$0.9476per unit
middle half $0.8662–$1.12 · 297 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $0.9476
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
5%of plans cover it
tier 3 · prior auth 45% · step therapy 0% · qty limit 84%
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for butalbital, acetaminophen, caffeine and codeine phosphate (oral solid) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- Bryant Ranch PrepackUnited Statesrelabel · repack
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- ANDA076560
- TE code
- AB
- Approval date
- Jun 10, 2004
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Butalbital, Acetaminophen, Caffeine and Codeine Phosphate (Capsule)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Bryant Ranch Prepack | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Breckenridge Pharmaceutical, Inc. | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Hikma Pharmaceuticals USA Inc. | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Hikma Pharmaceuticals USA Inc. | BUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| Breckenridge Pharmaceutical, Inc. | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Hikma Pharmaceuticals USA Inc. | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Hikma Pharmaceuticals USA Inc. | BUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Bryant Ranch Prepack | ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| Breckenridge Pharmaceutical, Inc. | ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Hikma Pharmaceuticals USA Inc. | ACETAMINOPHEN 300 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Hikma Pharmaceuticals USA Inc. | ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1; CODEINE PHOSPHATE 30 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Butalbital, Acetaminophen, Caffeine and Codeine Phosphate — NDC 71335-0194-01," retrieved September 3, 2026, https://drugdashboards.com/drug/71335019401.
Free to cite with attribution — see how the data is put together.