Promethazine Hydrochloride and Dextromethorphan Hydrobromide · PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL · Syrup · Oral · Xttrium Laboratories, Inc
NDC 00116-4024-16 · 473 mL in 1 BOTTLE, PLASTIC · ANDA · View full market →
Just 3 companies supply this market — thin enough that a single exit would be felt immediately. The price is down 16% over the past year, to $0.0384 per mL. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.
Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Some pressure is visible, but not much — here’s everything the score found to count.
The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| A-S Medication Solutions | PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| Atlantic Biologicals Corp. | PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| Xttrium Laboratories, Inc | PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| A-S Medication Solutions | PROMETHAZINE HYDROCHLORIDE 15 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 6.25 mg/5mL | Jul 22, 2026 | Aug 22, 2026 |
| Atlantic Biologicals Corp. | PROMETHAZINE HYDROCHLORIDE 15 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 6.25 mg/5mL | Jul 22, 2026 | Aug 19, 2026 |
| Xttrium Laboratories, Inc | PROMETHAZINE HYDROCHLORIDE 15 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 6.25 mg/5mL | Jul 22, 2026 | Aug 19, 2026 |
| A-S Medication Solutions | DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL; PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL | Jul 15, 2026 | Jul 19, 2026 |
| Atlantic Biologicals Corp. | DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL; PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL | Jul 15, 2026 | Jul 15, 2026 |
| Xttrium Laboratories, Inc | DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL; PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Promethazine Hydrochloride and Dextromethorphan Hydrobromide — NDC 00116-4024-16," retrieved September 3, 2026, https://drugdashboards.com/drug/00116402416.
Free to cite with attribution — see how the data is put together.