The short version
Just 3 companies supply this market — thin enough that a single exit would be felt immediately.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Promethazine Hydrochloride and Dextromethorphan Hydrobromide
promethazine hydrochloride and dextromethorphan hydrobromide · PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL · Syrup · Oral · A-S Medication Solutions
NDC 50090-6467-00 · 473 mL in 1 BOTTLE, PLASTIC · ANDA · View full market →
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for promethazine hydrochloride and dextromethorphan hydrobromide (other) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- A-S Medication Solutions LLCUnited Statesrelabel
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Regulatory
- Application
- ANDA088864
- TE code
- AA
- Approval date
- Jan 4, 1985
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of promethazine hydrochloride and dextromethorphan hydrobromide (Syrup)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| A-S Medication Solutions | PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| Atlantic Biologicals Corp. | PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| Xttrium Laboratories, Inc | PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL | Aug 26, 2026 | Sep 2, 2026 |
| A-S Medication Solutions | PROMETHAZINE HYDROCHLORIDE 15 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 6.25 mg/5mL | Jul 22, 2026 | Aug 22, 2026 |
| Atlantic Biologicals Corp. | PROMETHAZINE HYDROCHLORIDE 15 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 6.25 mg/5mL | Jul 22, 2026 | Aug 19, 2026 |
| Xttrium Laboratories, Inc | PROMETHAZINE HYDROCHLORIDE 15 mg/5mL; DEXTROMETHORPHAN HYDROBROMIDE 6.25 mg/5mL | Jul 22, 2026 | Aug 19, 2026 |
| A-S Medication Solutions | DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL; PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL | Jul 15, 2026 | Jul 19, 2026 |
| Atlantic Biologicals Corp. | DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL; PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL | Jul 15, 2026 | Jul 15, 2026 |
| Xttrium Laboratories, Inc | DEXTROMETHORPHAN HYDROBROMIDE 15 mg/5mL; PROMETHAZINE HYDROCHLORIDE 6.25 mg/5mL | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Promethazine Hydrochloride and Dextromethorphan Hydrobromide — NDC 50090-6467-00," retrieved September 3, 2026, https://drugdashboards.com/drug/50090646700.
Free to cite with attribution — see how the data is put together.