DrugDashboards

Clinimix E

Leucine, Phenylalanine, Lysine, Methionine, Isoleucine, Valine, Histidine, Threonine, Tryptophan, Alanine, Glycine, Arginine, Proline, Serine, Tyrosine, Sodium Acetate, Dibasic Potassium Phosphate, Magnesium Chloride, Sodium Chloride, Calcium Chloride, Dextrose · LEUCINE 311 mg/100mL; PHENYLALANINE 238 mg/100mL; LYSINE 247 mg/100mL; METHIONINE 170 mg/100mL; ISOLEUCINE 255 mg/100mL; VALINE 247 mg/100mL; HISTIDINE 204 mg/100mL; THREONINE 179 mg/100mL; TRYPTOPHAN 77 mg/100mL; ALANINE 880 mg/100mL; GLYCINE 438 mg/100mL; ARGININE 489 mg/100mL; PROLINE 289 mg/100mL; SERINE 213 mg/100mL; TYROSINE 17 mg/100mL; SODIUM ACETATE 297 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 261 mg/100mL; MAGNESIUM CHLORIDE 51 mg/100mL; SODIUM CHLORIDE 77 mg/100mL; CALCIUM CHLORIDE 33 mg/100mL; DEXTROSE 10 g/100mL · Injection · Intravenous · Baxter Healthcare Company

NDC 00338-1145-03 · 1000 mL in 1 BAG · NDA · View full market →

The short version

Only one company currently supplies this market — there is no backup if it stumbles. One of its named manufacturing plants, Baxter Healthcare Corporation, failed FDA inspectionwithin the last two years — the agency’s most serious outcome.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Part D plans paid (avg)$0.0448per dosage unitgross, before rebates — matched by drug name · 2024
  • Part D point of sale (median)$0.0476per unitnegotiated price across 1,419 plans — before rebates · Apr 1, 2026
  • Federal contracts pay (FSS)$129.96per package of 6X1000MLBaxter Healthcare Corporation · Sep 17, 2025

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.0476per unit
middle half $0.0476$0.0476 · 1,419 plans · Apr 1, 2026
Est. net of rebates
$0.0286–$0.0357
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
26%of plans cover it
tier 4 · prior auth 91% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed
$47.56
Reported to Texas DSHS · 2026 annual filing · Baxter Healthcare Corporation

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2024)

$3,910
21 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier · median tier 4 across plans
  • Costs ≥ $950/fill · avg $359.99 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA020678
TE code
Approval date
Mar 26, 1997
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class I · TerminatedJan 21, 2016
    Baxter Healthcare Corp.Presence of Particulate Matter: identified as dried skin.
  • Class II · TerminatedMar 23, 2015
    Baxter Healthcare CorpLack of Assurance of Sterility; increased complaints received for leaks
  • Class II · TerminatedNov 25, 2014
    Baxter Healthcare Corp.Lack of Assurance of Sterility; leaks were observed from the bag seam and port seal
  • Class I · TerminatedNov 18, 2013
    Baxter Healthcare Corp.Presence of Particulate Matter: Particulate matter includes wood, sodium citrate and dextrose.
  • Class I · TerminatedNov 18, 2013
    Baxter Healthcare Corp.Presence of Particulate Matter: Particulate matter includes wood, sodium citrate and dextrose.

Manufacturers of Leucine, Phenylalanine, Lysine, Methionine, Isoleucine, Valine, Histidine, Threonine, Tryptophan, Alanine, Glycine, Arginine, Proline, Serine, Tyrosine, Sodium Acetate, Dibasic Potassium Phosphate, Magnesium Chloride, Sodium Chloride, Calcium Chloride, Dextrose (Injection)

LabelerStrengthFirst seenLast seen
Baxter Healthcare CompanyALANINE 1035 mg/100mL; ARGININE 575 mg/100mL; CALCIUM CHLORIDE 33 mg/100mL; DEXTROSE 20 g/100mL; GLYCINE 515 mg/100mL; HISTIDINE 240 mg/100mL; ISOLEUCINE 300 mg/100mL; LEUCINE 365 mg/100mL; LYSINE 290 mg/100mL; MAGNESIUM CHLORIDE 51 mg/100mL; METHIONINE 200 mg/100mL; PHENYLALANINE 280 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 261 mg/100mL; PROLINE 340 mg/100mL; SERINE 250 mg/100mL; SODIUM ACETATE 340 mg/100mL; SODIUM CHLORIDE 59 mg/100mL; THREONINE 210 mg/100mL; TRYPTOPHAN 90 mg/100mL; TYROSINE 20 mg/100mL; VALINE 290 mg/100mLJul 15, 2026Sep 3, 2026
Baxter Healthcare CompanyALANINE 880 mg/100mL; ARGININE 489 mg/100mL; CALCIUM CHLORIDE 33 mg/100mL; DEXTROSE 5 g/100mL; GLYCINE 438 mg/100mL; HISTIDINE 204 mg/100mL; ISOLEUCINE 255 mg/100mL; LEUCINE 311 mg/100mL; LYSINE 247 mg/100mL; MAGNESIUM CHLORIDE 51 mg/100mL; METHIONINE 170 mg/100mL; PHENYLALANINE 238 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 261 mg/100mL; PROLINE 289 mg/100mL; SERINE 213 mg/100mL; SODIUM ACETATE 297 mg/100mL; SODIUM CHLORIDE 77 mg/100mL; THREONINE 179 mg/100mL; TRYPTOPHAN 77 mg/100mL; TYROSINE 17 mg/100mL; VALINE 247 mg/100mLJul 15, 2026Sep 3, 2026
Baxter Healthcare CompanyALANINE 570 mg/100mL; ARGININE 316 mg/100mL; CALCIUM CHLORIDE 33 mg/100mL; DEXTROSE 5 g/100mL; GLYCINE 283 mg/100mL; HISTIDINE 132 mg/100mL; ISOLEUCINE 165 mg/100mL; LEUCINE 201 mg/100mL; LYSINE 159 mg/100mL; MAGNESIUM CHLORIDE 51 mg/100mL; METHIONINE 110 mg/100mL; PHENYLALANINE 154 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 261 mg/100mL; PROLINE 187 mg/100mL; SERINE 138 mg/100mL; SODIUM ACETATE 216 mg/100mL; SODIUM CHLORIDE 112 mg/100mL; THREONINE 116 mg/100mL; TRYPTOPHAN 50 mg/100mL; TYROSINE 11 mg/100mL; VALINE 160 mg/100mLJul 15, 2026Sep 2, 2026
Baxter Healthcare CompanyALANINE 570 mg/100mL; ARGININE 316 mg/100mL; CALCIUM CHLORIDE 33 mg/100mL; DEXTROSE 5 g/100mL; GLYCINE 283 mg/100mL; HISTIDINE 132 mg/100mL; ISOLEUCINE 165 mg/100mL; LEUCINE 201 mg/100mL; LYSINE 159 mg/100mL; MAGNESIUM CHLORIDE 51 mg/100mL; METHIONINE 110 mg/100mL; PHENYLALANINE 154 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 261 mg/100mL; PROLINE 187 mg/100mL; SERINE 138 mg/100mL; SODIUM ACETATE 217 mg/100mL; SODIUM CHLORIDE 112 mg/100mL; THREONINE 116 mg/100mL; TRYPTOPHAN 50 mg/100mL; TYROSINE 11 mg/100mL; VALINE 160 mg/100mLJul 15, 2026Sep 2, 2026
Baxter Healthcare CompanyALANINE 1035 mg/100mL; ARGININE 575 mg/100mL; CALCIUM CHLORIDE 33 mg/100mL; DEXTROSE 15 g/100mL; GLYCINE 515 mg/100mL; HISTIDINE 240 mg/100mL; ISOLEUCINE 300 mg/100mL; LEUCINE 365 mg/100mL; LYSINE 290 mg/100mL; MAGNESIUM CHLORIDE 51 mg/100mL; METHIONINE 200 mg/100mL; PHENYLALANINE 280 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 261 mg/100mL; PROLINE 340 mg/100mL; SERINE 250 mg/100mL; SODIUM ACETATE 340 mg/100mL; SODIUM CHLORIDE 59 mg/100mL; THREONINE 210 mg/100mL; TRYPTOPHAN 90 mg/100mL; TYROSINE 20 mg/100mL; VALINE 290 mg/100mLJul 15, 2026Aug 31, 2026
Baxter Healthcare CompanyALANINE 880 mg/100mL; ARGININE 489 mg/100mL; CALCIUM CHLORIDE 33 mg/100mL; DEXTROSE 10 g/100mL; GLYCINE 438 mg/100mL; HISTIDINE 204 mg/100mL; ISOLEUCINE 255 mg/100mL; LEUCINE 311 mg/100mL; LYSINE 247 mg/100mL; MAGNESIUM CHLORIDE 51 mg/100mL; METHIONINE 170 mg/100mL; PHENYLALANINE 238 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 261 mg/100mL; PROLINE 289 mg/100mL; SERINE 213 mg/100mL; SODIUM ACETATE 297 mg/100mL; SODIUM CHLORIDE 77 mg/100mL; THREONINE 179 mg/100mL; TRYPTOPHAN 77 mg/100mL; TYROSINE 17 mg/100mL; VALINE 247 mg/100mLJul 15, 2026Aug 31, 2026
Baxter Healthcare CompanyALANINE 51 mg/100mL; ARGININE 280 mg/100mL; CALCIUM CHLORIDE 20 mg/100mL; DEXTROSE 290 mg/100mL; GLYCINE 200 mg/100mL; HISTIDINE 300 mg/100mL; ISOLEUCINE 515 mg/100mL; LEUCINE 1035 mg/100mL; LYSINE 33 mg/100mL; MAGNESIUM CHLORIDE 210 mg/100mL; METHIONINE 15 g/100mL; PHENYLALANINE 575 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 59 mg/100mL; PROLINE 261 mg/100mL; SERINE 340 mg/100mL; SODIUM ACETATE 340 mg/100mL; SODIUM CHLORIDE 90 mg/100mL; THREONINE 365 mg/100mL; TRYPTOPHAN 290 mg/100mL; TYROSINE 250 mg/100mL; VALINE 240 mg/100mLJul 22, 2026Aug 22, 2026
Baxter Healthcare CompanyALANINE 51 mg/100mL; ARGININE 280 mg/100mL; CALCIUM CHLORIDE 20 mg/100mL; DEXTROSE 290 mg/100mL; GLYCINE 200 mg/100mL; HISTIDINE 300 mg/100mL; ISOLEUCINE 515 mg/100mL; LEUCINE 1035 mg/100mL; LYSINE 33 mg/100mL; MAGNESIUM CHLORIDE 210 mg/100mL; METHIONINE 20 g/100mL; PHENYLALANINE 575 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 59 mg/100mL; PROLINE 261 mg/100mL; SERINE 340 mg/100mL; SODIUM ACETATE 340 mg/100mL; SODIUM CHLORIDE 90 mg/100mL; THREONINE 365 mg/100mL; TRYPTOPHAN 290 mg/100mL; TYROSINE 250 mg/100mL; VALINE 240 mg/100mLJul 22, 2026Aug 22, 2026
Baxter Healthcare CompanyALANINE 51 mg/100mL; ARGININE 238 mg/100mL; CALCIUM CHLORIDE 17 mg/100mL; DEXTROSE 247 mg/100mL; GLYCINE 170 mg/100mL; HISTIDINE 255 mg/100mL; ISOLEUCINE 438 mg/100mL; LEUCINE 880 mg/100mL; LYSINE 33 mg/100mL; MAGNESIUM CHLORIDE 179 mg/100mL; METHIONINE 10 g/100mL; PHENYLALANINE 489 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 77 mg/100mL; PROLINE 261 mg/100mL; SERINE 289 mg/100mL; SODIUM ACETATE 297 mg/100mL; SODIUM CHLORIDE 77 mg/100mL; THREONINE 311 mg/100mL; TRYPTOPHAN 247 mg/100mL; TYROSINE 213 mg/100mL; VALINE 204 mg/100mLJul 22, 2026Aug 22, 2026
Baxter Healthcare CompanyALANINE 51 mg/100mL; ARGININE 238 mg/100mL; CALCIUM CHLORIDE 17 mg/100mL; DEXTROSE 247 mg/100mL; GLYCINE 170 mg/100mL; HISTIDINE 255 mg/100mL; ISOLEUCINE 438 mg/100mL; LEUCINE 880 mg/100mL; LYSINE 33 mg/100mL; MAGNESIUM CHLORIDE 179 mg/100mL; METHIONINE 5 g/100mL; PHENYLALANINE 489 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 77 mg/100mL; PROLINE 261 mg/100mL; SERINE 289 mg/100mL; SODIUM ACETATE 297 mg/100mL; SODIUM CHLORIDE 77 mg/100mL; THREONINE 311 mg/100mL; TRYPTOPHAN 247 mg/100mL; TYROSINE 213 mg/100mL; VALINE 204 mg/100mLJul 22, 2026Aug 22, 2026
Baxter Healthcare CompanyALANINE 51 mg/100mL; ARGININE 154 mg/100mL; CALCIUM CHLORIDE 11 mg/100mL; DEXTROSE 160 mg/100mL; GLYCINE 110 mg/100mL; HISTIDINE 165 mg/100mL; ISOLEUCINE 283 mg/100mL; LEUCINE 570 mg/100mL; LYSINE 33 mg/100mL; MAGNESIUM CHLORIDE 116 mg/100mL; METHIONINE 5 g/100mL; PHENYLALANINE 316 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 112 mg/100mL; PROLINE 261 mg/100mL; SERINE 187 mg/100mL; SODIUM ACETATE 217 mg/100mL; SODIUM CHLORIDE 50 mg/100mL; THREONINE 201 mg/100mL; TRYPTOPHAN 159 mg/100mL; TYROSINE 138 mg/100mL; VALINE 132 mg/100mLJul 22, 2026Aug 19, 2026
Baxter Healthcare CompanyALANINE 51 mg/100mL; ARGININE 154 mg/100mL; CALCIUM CHLORIDE 11 mg/100mL; DEXTROSE 160 mg/100mL; GLYCINE 110 mg/100mL; HISTIDINE 165 mg/100mL; ISOLEUCINE 283 mg/100mL; LEUCINE 570 mg/100mL; LYSINE 33 mg/100mL; MAGNESIUM CHLORIDE 116 mg/100mL; METHIONINE 5 g/100mL; PHENYLALANINE 316 mg/100mL; POTASSIUM PHOSPHATE, DIBASIC 112 mg/100mL; PROLINE 261 mg/100mL; SERINE 187 mg/100mL; SODIUM ACETATE 216 mg/100mL; SODIUM CHLORIDE 50 mg/100mL; THREONINE 201 mg/100mL; TRYPTOPHAN 159 mg/100mL; TYROSINE 138 mg/100mL; VALINE 132 mg/100mLJul 22, 2026Aug 19, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Clinimix E — NDC 00338-1145-03," retrieved September 4, 2026, https://drugdashboards.com/drug/00338114503.

Free to cite with attribution — see how the data is put together.