Brimonidine Tartrate and Timolol Maleate · BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mL · Solution/ Drops · Ophthalmic · Sandoz Inc
NDC 00781-7186-70 · 1 BOTTLE in 1 CARTON / 10 mL in 1 BOTTLE · ANDA · View full market →
9 companies supply this market — a reasonable cushion if one runs into trouble. The price has fallen 52% in a year, to $2.46 per mL — and generics that get this cheap tend to get abandoned rather than defended. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Matched to CMS's representative package for this drug (NDC 00832-1425-05) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 1 quarter since 2024.
Manufacturer list price as filed — not what pharmacies actually pay after discounts.
Some pressure is visible, but not much — here’s everything the score found to count.
The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026
OAI inspection at a producing facility (24 months) · sole-source market · 2 Class I/II recall(s) in 12 months
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Gland Pharma Limited | BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mL | Jul 15, 2026 | Sep 3, 2026 |
| Alembic Pharmaceuticals Inc. | BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Alembic Pharmaceuticals Limited | BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Armas Pharmaceuticals Inc | BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Glenmark Pharmaceuticals Inc., USA | BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| NorthStar RxLLC | BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Sandoz Inc | BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Upsher-Smith Laboratories, LLC | BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mL | Jul 15, 2026 | Sep 2, 2026 |
| Somerset Therapeutics, LLC | BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mL | Jul 15, 2026 | Aug 31, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Brimonidine Tartrate and Timolol Maleate — NDC 00781-7186-70," retrieved September 3, 2026, https://drugdashboards.com/drug/00781718670.
Free to cite with attribution — see how the data is put together.