DrugDashboards

Brimonidine Tartrate and Timolol Maleate

Brimonidine Tartrate and Timolol Maleate · BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mL · Solution/ Drops · Ophthalmic · Upsher-Smith Laboratories, LLC

NDC 00832-1425-05 · 1 BOTTLE, DROPPER in 1 CARTON / 5 mL in 1 BOTTLE, DROPPER · ANDA · View full market →

The short version

9 companies supply this market — a reasonable cushion if one runs into trouble. The price has fallen 46% in a year, to $2.79 per mL — and generics that get this cheap tend to get abandoned rather than defended. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$2.79per MLinvoice-surveyed acquisition cost · Aug 19, 2026
  • Part D point of sale (median)$10.31per unitnegotiated price across 3,040 plans — before rebates · Apr 1, 2026
  • Federal contracts pay (FSS)$16.69per package of 5MLThe Davinci Company, LLC · Jul 18, 2025

Medicare Part D

All Part D pricing →
ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$10.31per unit
middle half $9.54$13.97 · 3,040 plans · Apr 1, 2026
Est. net of rebates
≈ $10.31
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
55%of plans cover it
tier 3 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 1 quarter since 2024.

NADAC price per unit

$0$10.00$20.00May 2023Sep 2026$2.79
41 price points · per MLSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$127.99
Reported to Texas DSHS · 2026 annual filing · Upsher-Smith Laboratories, Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$426,528
5,686 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

15Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • price down 41% year over year+15

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for brimonidine tartrate and timolol maleate (other) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market · 2 Class I/II recall(s) in 12 months

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA215598
TE code
AB
Approval date
Dec 12, 2022
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Brimonidine Tartrate and Timolol Maleate (Solution/ Drops)

LabelerStrengthFirst seenLast seen
Gland Pharma LimitedBRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 3, 2026
Alembic Pharmaceuticals Inc.BRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Alembic Pharmaceuticals LimitedBRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Armas Pharmaceuticals IncBRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Glenmark Pharmaceuticals Inc., USABRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
NorthStar RxLLCBRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Sandoz IncBRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Upsher-Smith Laboratories, LLCBRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Sep 2, 2026
Somerset Therapeutics, LLCBRIMONIDINE TARTRATE 2 mg/mL; TIMOLOL MALEATE 5 mg/mLJul 15, 2026Aug 31, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Brimonidine Tartrate and Timolol Maleate — NDC 00832-1425-05," retrieved September 3, 2026, https://drugdashboards.com/drug/00832142505.

Free to cite with attribution — see how the data is put together.