DrugDashboards

Heparin Sodium

heparin sodium · HEPARIN SODIUM 20000 [USP'U]/mL · Injection · Intravenous; Subcutaneous · Sagent Pharmaceuticals

NDC 25021-0404-01 · 25 VIAL in 1 CARTON / 1 mL in 1 VIAL · ANDA · View full market →

The short version

13 companies supply this market — deep enough that no single failure threatens the supply. The generic price is up 10% over the past year, to $7.62 per mL. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want. Historically, drugs in this position went on to a new shortage within 90 days about 0.6% of the time — roughly 4× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$7.62per MLinvoice-surveyed acquisition cost · Jul 23, 2025
  • Medicare Part B pays (ASP+6%)$0.1990per billing unit (1000 UNITS)HCPCS J1644 · Jul 1, 2026
  • Part D plans paid (avg)$2.01per dosage unitgross, before rebates — matched by drug name · 2024

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$5.00$10.00$15.00Nov 2013Jul 2025$7.62
8 price points · per ML · last surveyed Invalid DateSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$250.00
Reported to Texas DSHS · 2026 annual filing · Sagent Pharmaceuticals

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicare Part B (ASP)

Payment limit per 1000 UNITS
$0.199
HCPCS J1644 · Jul 1, 2026 quarter · typically ASP + 6%

Medicaid spend (2025)

$4,196
143 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

10Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • sterile injectable+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.6%chance of a new FDA shortage posting for heparin sodium (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 4× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $54.61 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA090809
TE code
AP
Approval date
Jun 30, 2010
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class II · TerminatedFeb 28, 2023
    Sagent Pharmaceuticals IncLabeling: Not elsewhere classified

Manufacturers of heparin sodium (Injection)

LabelerStrengthFirst seenLast seen
Meitheal Pharmaceuticals Inc.HEPARIN SODIUM 10000 [USP'U]/mLJul 15, 2026Sep 3, 2026
NorthStar RxLLCHEPARIN SODIUM 5000 [USP'U]/mLJul 15, 2026Sep 3, 2026
NorthStar RxLLCHEPARIN SODIUM 1000 [USP'U]/mLJul 15, 2026Sep 3, 2026
Cardinal Health 107, LLCHEPARIN SODIUM 5000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Civica, Inc.HEPARIN SODIUM 5000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Civica, Inc.HEPARIN SODIUM 1000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Gland Pharma LimitedHEPARIN SODIUM 5000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.HEPARIN SODIUM 10000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.HEPARIN SODIUM 5000 [USP'U]/.5mLJul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.HEPARIN SODIUM 1000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Medical Purchasing Solutions, LLCHEPARIN SODIUM 1000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Medical Purchasing Solutions, LLC.HEPARIN SODIUM 1000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Meitheal Pharmaceuticals Inc.HEPARIN SODIUM 2000 [USP'U]/2mLJul 15, 2026Sep 2, 2026
Meitheal Pharmaceuticals Inc.HEPARIN SODIUM 20000 [USP'U]/mLJul 15, 2026Sep 2, 2026
NorthStar RxLLCHEPARIN SODIUM 20000 [USP'U]/mLJul 15, 2026Sep 2, 2026
NorthStar RxLLCHEPARIN SODIUM 2000 [USP'U]/2mLJul 15, 2026Sep 2, 2026
NorthStar RxLLCHEPARIN SODIUM 10000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Pfizer Laboratories Div Pfizer IncHEPARIN SODIUM 1000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Plano Pharmaceuticals Inc.HEPARIN SODIUM 5000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Remedyrepack Inc.HEPARIN SODIUM 5000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Sagent PharmaceuticalsHEPARIN SODIUM 20000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Sagent PharmaceuticalsHEPARIN SODIUM 1000 [USP'U]/mLJul 15, 2026Sep 2, 2026
Gland Pharma LimitedHEPARIN SODIUM 1000 [USP'U]/mLJul 15, 2026Aug 31, 2026
Hikma Pharmaceuticals USA Inc.HEPARIN SODIUM 5000 [USP'U]/mLJul 15, 2026Aug 31, 2026
Meitheal Pharmaceuticals Inc.HEPARIN SODIUM 5000 [USP'U]/mLJul 15, 2026Aug 31, 2026
Meitheal Pharmaceuticals Inc.HEPARIN SODIUM 1000 [USP'U]/mLJul 15, 2026Aug 31, 2026
Mylan Institutional LLCHEPARIN SODIUM 1000 [USP'U]/mLJul 15, 2026Aug 29, 2026
Mylan Institutional LLCHEPARIN SODIUM 5000 [USP'U]/mLJul 15, 2026Jul 31, 2026
Mylan Institutional LLCHEPARIN SODIUM 10000 [USP'U]/mLJul 15, 2026Jul 29, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Heparin Sodium — NDC 25021-0404-01," retrieved September 3, 2026, https://drugdashboards.com/drug/25021040401.

Free to cite with attribution — see how the data is put together.