DrugDashboards

Daptomycin

Daptomycin · DAPTOMYCIN 350 mg/7mL · Injection, Powder, Lyophilized, For Solution · Intravenous · Camber Pharmaceuticals, Inc.

NDC 31722-0215-01 · 1 VIAL, SINGLE-DOSE in 1 CARTON / 7 mL in 1 VIAL, SINGLE-DOSE · ANDA · View full market →

The short version

25 companies supply this market — deep enough that no single failure threatens the supply. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want. Historically, drugs in this position went on to a new shortage within 90 days about 0.5% of the time — roughly 3× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$13.42per EAinvoice-surveyed acquisition cost · Jul 23, 2025
  • Part D plans paid (avg)$50.13per dosage unitgross, before rebates — matched by drug name · 2024

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 16729-0434-45) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$65.35per unit
middle half $28.84$171.87 · 4,515 plans · Apr 1, 2026
Est. net of rebates
≈ $65.35
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
82%of plans cover it
tier 4 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$10.00$20.00Dec 2024Jul 2025$13.42
8 price points · per EA · last surveyed Invalid DateSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$30.00
Reported to Texas DSHS · 2026 annual filing · Aspiro Pharma Limited

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$5,286
23 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

10Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • sterile injectable+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.5%chance of a new FDA shortage posting for daptomycin (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 3× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $790.29 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA216445
TE code
AP
Approval date
Dec 23, 2022
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation Daptomycin, Injection, 500 mg/10 mL (NDC 0143-9378-01)Jun 30, 2026

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Daptomycin (Injection, Powder, Lyophilized, For Solution)

LabelerStrengthFirst seenLast seen
Fresenius Kabi USA, LLCDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 3, 2026
Hikma Pharmaceuticals USA Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 3, 2026
Meitheal Pharmaceuticals Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 3, 2026
Meitheal Pharmaceuticals Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 3, 2026
Mylan Institutional LLCDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 3, 2026
Sagent PharmaceuticalsDAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 3, 2026
Xellia Pharmaceuticals USA LLCDAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 3, 2026
Xellia Pharmaceuticals USA LLCDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 3, 2026
Accord Healthcare Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Accord Healthcare, Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
Apotex Corp.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
BE Pharmaceuticals Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
BE Pharmaceuticals Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Biocon Pharma Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
BluePoint LaboratoriesDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
Civica, Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
Dr. Reddy's Laboratories Inc.,DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
Dr.Reddy's Laboratories Inc.,DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Eugia US LLCDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Hospira, Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Hospira, Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
MAIA Pharmaceuticals, Inc.DAPTOMYCIN 500 mg/1Jul 15, 2026Sep 2, 2026
NorthStar RxLLCDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
NorthStar RxLLCDAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
Par Health USA, LLCDAPTOMYCIN 500 mg/1Jul 15, 2026Sep 2, 2026
Patheon Italia S.p.ADAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Patheon Italia S.p.A.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Qilu Pharmaceutical Co., Ltd.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Sagent PharmaceuticalsDAPTOMYCIN 50 mg/mLJul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Aug 31, 2026
Aspiro Pharma LimitedDAPTOMYCIN 500 mg/10mLAug 28, 2026Aug 28, 2026
Civica, Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Daptomycin — NDC 31722-0215-01," retrieved September 3, 2026, https://drugdashboards.com/drug/31722021501.

Free to cite with attribution — see how the data is put together.