DrugDashboards

Daptomycin

Daptomycin · DAPTOMYCIN 500 mg/1 · Injection, Powder, Lyophilized, For Solution · Intravenous · Par Health USA, LLC

NDC 42023-0295-10 · 10 VIAL, SINGLE-DOSE in 1 CARTON / 1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION in 1 VIAL, SINGLE-DOSE · NDA · View full market →

The short version

25 companies supply this market — deep enough that no single failure threatens the supply. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want. Historically, drugs in this position went on to a new shortage within 90 days about 0.5% of the time — roughly 3× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$20.77per EAinvoice-surveyed acquisition cost · Jan 21, 2026
  • Part D plans paid (avg)$50.13per dosage unitgross, before rebates — matched by drug name · 2024
  • Federal ceiling (Big4)$226.13per unitEndo USA, Inc. · Feb 3, 20261089% of what pharmacies pay — higher than 95% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$10.00$20.00$30.00Dec 2025Jan 2026$20.77
3 price points · per EA · last surveyed Invalid DateSource: CMS NADAC

Estimated fill cost

WAC per package, as filed
$4,450.00
Reported to Texas DSHS · 2026 annual filing · Par Health USA, LLC

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Supply fragility

10● Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • sterile injectable+10

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.5%chance of a new FDA shortage posting for daptomycin (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 3× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill · avg $790.29 per prescription
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
NDA217630
TE code
—
Approval date
Nov 21, 2024
Patents / exclusivity
None on file

Shortage history

  • Planned discontinuation — Daptomycin, Injection, 500 mg/10 mL (NDC 0143-9378-01)Jun 30, 2026

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Daptomycin (Injection, Powder, Lyophilized, For Solution)

LabelerStrengthFirst seenLast seen
Fresenius Kabi USA, LLCDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 3, 2026
Hikma Pharmaceuticals USA Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 3, 2026
Meitheal Pharmaceuticals Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 3, 2026
Meitheal Pharmaceuticals Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 3, 2026
Mylan Institutional LLCDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 3, 2026
Sagent PharmaceuticalsDAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 3, 2026
Xellia Pharmaceuticals USA LLCDAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 3, 2026
Xellia Pharmaceuticals USA LLCDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 3, 2026
Accord Healthcare Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Accord Healthcare, Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
Apotex Corp.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
BE Pharmaceuticals Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
BE Pharmaceuticals Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Biocon Pharma Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
BluePoint LaboratoriesDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
Civica, Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
Dr. Reddy's Laboratories Inc.,DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
Dr.Reddy's Laboratories Inc.,DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Eugia US LLCDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Hospira, Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Hospira, Inc.DAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
MAIA Pharmaceuticals, Inc.DAPTOMYCIN 500 mg/1Jul 15, 2026Sep 2, 2026
NorthStar RxLLCDAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
NorthStar RxLLCDAPTOMYCIN 350 mg/7mLJul 15, 2026Sep 2, 2026
Par Health USA, LLCDAPTOMYCIN 500 mg/1Jul 15, 2026Sep 2, 2026
Patheon Italia S.p.ADAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Patheon Italia S.p.A.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Qilu Pharmaceutical Co., Ltd.DAPTOMYCIN 500 mg/10mLJul 15, 2026Sep 2, 2026
Sagent PharmaceuticalsDAPTOMYCIN 50 mg/mLJul 15, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Aug 31, 2026
Aspiro Pharma LimitedDAPTOMYCIN 500 mg/10mLAug 28, 2026Aug 28, 2026
Civica, Inc.DAPTOMYCIN 500 mg/10mLJul 15, 2026Aug 28, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Daptomycin — NDC 42023-0295-10," retrieved September 3, 2026, https://drugdashboards.com/drug/42023029510.

Free to cite with attribution — see how the data is put together.