DrugDashboards

Bupropion Hydrochloride (XL)

bupropion hydrochloride · BUPROPION HYDROCHLORIDE 150 mg/1 · Tablet, Film Coated, Extended Release · Oral · Dr Reddys Laboratories Inc

NDC 43598-0655-05 · 500 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE, PLASTIC · ANDA · View full market →

The short version

22 companies supply this market — deep enough that no single failure threatens the supply. The price is down 29% over the past year, to $0.1054 per unit.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00591-3543-60) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.3912per unit
middle half $0.2688$0.5542 · 5,496 plans · Apr 1, 2026
Est. net of rebates
≈ $0.3912
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 2 · prior auth 0% · step therapy 0% · qty limit 64%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.5$1.00Oct 2017Feb 2023$0.1054
65 price points · per · last surveyed Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

WAC per package, as filed
$208.33
Reported to Texas DSHS · 2023 annual filing · Dr. Reddy's Laboratories, Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2022)

$140
31 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for bupropion hydrochloride (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market · 1 Class I/II recall(s) in 12 months

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA207479
TE code
AB3
Approval date
Apr 12, 2017
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of bupropion hydrochloride (Tablet, Film Coated, Extended Release)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Aphena Pharma Solutions - Tennessee, LLCBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 3, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 3, 2026
Dr. Reddys Laboratories Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 3, 2026
Dr. Reddys Laboratories Inc.BUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 3, 2026
Proficient Rx LPBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Remedyrepack Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 3, 2026
Remedyrepack Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
ScieGen Pharmaceuticals, Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Upsher-Smith Laboratories, LLCBUPROPION HYDROCHLORIDE 450 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Actavis Pharma, Inc.BUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Actavis Pharma, Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Advanced Rx of Tennessee, LLCBUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Aphena Pharma Solutions - Tennessee, LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Asclemed USA, Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 300 mg/1Aug 5, 2026Sep 2, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Cardinal Health 107, LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA., Inc.BUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA., Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Dr Reddys Laboratories IncBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Dr Reddys Laboratories IncBUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026
Epic Pharma, LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.BUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals, Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals,Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Bupropion Hydrochloride (XL) — NDC 43598-0655-05," retrieved September 3, 2026, https://drugdashboards.com/drug/43598065505.

Free to cite with attribution — see how the data is put together.