DrugDashboards

Bupropion Hydrochloride (XL)

bupropion hydrochloride · BUPROPION HYDROCHLORIDE 300 mg/1 · Tablet, Film Coated, Extended Release · Oral · Dr Reddys Laboratories Inc

NDC 43598-0656-05 · 500 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE, PLASTIC · ANDA · View full market →

The short version

22 companies supply this market — deep enough that no single failure threatens the supply. The price has fallen 32% in a year, to $0.1014 per unit — and generics that get this cheap tend to get abandoned rather than defended. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.1014per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicaid generic ceiling (FUL)$0.1964per TABweighted avg manufacturer price $0.1122 · Aug 1, 2026194% of what pharmacies pay — higher than 86% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.2$0.4$0.6Oct 2017Sep 2026$0.1014
108 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$3.04
#90 count
$9.12

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$316
24 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

8● Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • price down 32% year over year+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for bupropion hydrochloride (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market · 1 Class I/II recall(s) in 12 months

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA207479
TE code
AB3
Approval date
Apr 12, 2017
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of bupropion hydrochloride (Tablet, Film Coated, Extended Release)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Aphena Pharma Solutions - Tennessee, LLCBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 3, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 3, 2026
Dr. Reddys Laboratories Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 3, 2026
Dr. Reddys Laboratories Inc.BUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 3, 2026
Proficient Rx LPBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Remedyrepack Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 3, 2026
Remedyrepack Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
ScieGen Pharmaceuticals, Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Upsher-Smith Laboratories, LLCBUPROPION HYDROCHLORIDE 450 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Actavis Pharma, Inc.BUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Actavis Pharma, Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Advanced Rx of Tennessee, LLCBUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Aphena Pharma Solutions - Tennessee, LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Asclemed USA, Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 300 mg/1Aug 5, 2026Sep 2, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Cardinal Health 107, LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA., Inc.BUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA., Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Dr Reddys Laboratories IncBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Dr Reddys Laboratories IncBUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026
Epic Pharma, LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.BUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals, Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals,Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Bupropion Hydrochloride (XL) — NDC 43598-0656-05," retrieved September 3, 2026, https://drugdashboards.com/drug/43598065605.

Free to cite with attribution — see how the data is put together.