The short version
9 companies supply this market — a reasonable cushion if one runs into trouble.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Tramadol Hydrochloride and Acetaminophen
Tramadol Hydrochloride and Acetaminophen · TRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1 · Tablet, Film Coated · Oral · Medsource Pharmaceuticals
NDC 45865-0170-60 · 60 TABLET, FILM COATED in 1 BOTTLE · ANDA · View full market →
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for tramadol hydrochloride and acetaminophen (oral solid) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- analysis · manufacture
- Medsource PharmaceuticalsUnited Statesrepack
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- ANDA207152
- TE code
- AB
- Approval date
- Mar 22, 2017
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Tramadol Hydrochloride and Acetaminophen (Tablet, Film Coated)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Bryant Ranch Prepack | TRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Asclemed USA, Inc. | TRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | TRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Direct_Rx | ACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Medsource Pharmaceuticals | TRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Proficient Rx LP | TRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Remedyrepack Inc. | TRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| St. Mary's Medical Park Pharmacy | TRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | TRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| Asclemed USA, Inc. | TRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Aurobindo Pharma Limited | TRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Medsource Pharmaceuticals | TRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Proficient Rx LP | TRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Remedyrepack Inc. | TRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| St. Mary's Medical Park Pharmacy | TRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Micro Labs Limited | TRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1 | Jul 22, 2026 | Aug 5, 2026 |
| Bryant Ranch Prepack | ACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| Asclemed USA, Inc. | ACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Aurobindo Pharma Limited | ACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Medsource Pharmaceuticals | ACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Micro Labs Limited | ACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Proficient Rx LP | ACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Remedyrepack Inc. | ACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| St. Mary's Medical Park Pharmacy | ACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Tramadol Hydrochloride and Acetaminophen — NDC 45865-0170-60," retrieved September 3, 2026, https://drugdashboards.com/drug/45865017060.
Free to cite with attribution — see how the data is put together.