DrugDashboards

Tramadol Hydrochloride and Acetaminophen

Tramadol Hydrochloride and Acetaminophen · TRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1 · Tablet, Film Coated · Oral · Aurobindo Pharma Limited

NDC 65862-0922-01 · 100 TABLET, FILM COATED in 1 BOTTLE · ANDA · View full market →

The short version

9 companies supply this market — a reasonable cushion if one runs into trouble. The price has held steady around $0.1056 per unit over the past year. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.1056per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicaid generic ceiling (FUL)$0.1056per TABweighted avg manufacturer price $0.0475 · Aug 1, 2026100% of what pharmacies pay — higher than 10% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.1$0.2Dec 2017Sep 2026$0.1056
106 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$3.17
#90 count
$9.50

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$11,854
1,105 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for tramadol hydrochloride and acetaminophen (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
ANDA207152
TE code
AB
Approval date
Mar 22, 2017
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Tramadol Hydrochloride and Acetaminophen (Tablet, Film Coated)

LabelerStrengthFirst seenLast seen
Bryant Ranch PrepackTRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 3, 2026
Asclemed USA, Inc.TRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Aurobindo Pharma LimitedTRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Direct_RxACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1Jul 15, 2026Sep 2, 2026
Medsource PharmaceuticalsTRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Proficient Rx LPTRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Remedyrepack Inc.TRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
St. Mary's Medical Park PharmacyTRAMADOL HYDROCHLORIDE 37.5 mg/1; ACETAMINOPHEN 325 mg/1Aug 26, 2026Sep 2, 2026
Bryant Ranch PrepackTRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1Jul 22, 2026Aug 22, 2026
Asclemed USA, Inc.TRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1Jul 22, 2026Aug 19, 2026
Aurobindo Pharma LimitedTRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1Jul 22, 2026Aug 19, 2026
Medsource PharmaceuticalsTRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1Jul 22, 2026Aug 19, 2026
Proficient Rx LPTRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1Jul 22, 2026Aug 19, 2026
Remedyrepack Inc.TRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1Jul 22, 2026Aug 19, 2026
St. Mary's Medical Park PharmacyTRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1Jul 22, 2026Aug 19, 2026
Micro Labs LimitedTRAMADOL HYDROCHLORIDE 325 mg/1; ACETAMINOPHEN 37.5 mg/1Jul 22, 2026Aug 5, 2026
Bryant Ranch PrepackACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1Jul 15, 2026Jul 19, 2026
Asclemed USA, Inc.ACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1Jul 15, 2026Jul 15, 2026
Aurobindo Pharma LimitedACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1Jul 15, 2026Jul 15, 2026
Medsource PharmaceuticalsACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1Jul 15, 2026Jul 15, 2026
Micro Labs LimitedACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1Jul 15, 2026Jul 15, 2026
Proficient Rx LPACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1Jul 15, 2026Jul 15, 2026
Remedyrepack Inc.ACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1Jul 15, 2026Jul 15, 2026
St. Mary's Medical Park PharmacyACETAMINOPHEN 325 mg/1; TRAMADOL HYDROCHLORIDE 37.5 mg/1Jul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Tramadol Hydrochloride and Acetaminophen — NDC 65862-0922-01," retrieved September 3, 2026, https://drugdashboards.com/drug/65862092201.

Free to cite with attribution — see how the data is put together.