DrugDashboards

Bupropion hydrochloride

Bupropion hydrochloride · BUPROPION HYDROCHLORIDE 100 mg/1 · Tablet, Film Coated, Extended Release · Oral · Sun Pharmaceutical Industries, Inc.

NDC 47335-0736-86 · 60 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE · ANDA · View full market →

The short version

22 companies supply this market — deep enough that no single failure threatens the supply. The price is down 18% over the past year, to $0.0709 per unit. One of its named manufacturing plants, Sun Pharmaceutical Industries Limited, failed FDA inspectionwithin the last two years — the agency’s most serious outcome. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.0709per EAinvoice-surveyed acquisition cost · Feb 18, 2026
  • Medicaid generic ceiling (FUL)$0.0713per TABweighted avg manufacturer price $0.0296 · Jan 1, 2026101% of what pharmacies pay — higher than 57% of drugs with this benchmark

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 43547-0288-10) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.1960per unit
middle half $0.1128$0.3002 · 5,487 plans · Apr 1, 2026
Est. net of rebates
≈ $0.1960
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 2 · prior auth 0% · step therapy 0% · qty limit 72%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.1$0.2$0.3Nov 2013Feb 2026$0.0709
149 price points · per EA · last surveyed Feb 18, 2026 · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$2.13
#90 count
$6.38

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2023)

$3,112
253 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for bupropion hydrochloride (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market · 1 Class I/II recall(s) in 12 months

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
ANDA078866
TE code
Approval date
Apr 6, 2010
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

  • Class III · TerminatedNov 22, 2023
    SUN PHARMACEUTICAL INDUSTRIES INCFailed Dissolution Specifications
  • Class III · TerminatedOct 4, 2023
    SUN PHARMACEUTICAL INDUSTRIES INCFailed Dissolution Specifications
  • Class II · TerminatedMay 9, 2023
    SUN PHARMACEUTICAL INDUSTRIES INCFailed Dissolution Specifications; during stability testing
  • Class III · TerminatedApr 29, 2022
    SUN PHARMACEUTICAL INDUSTRIES INCPresence Of Foreign Substance: Customer complaint for the presence of dark, gritty substance found within the bottle which was determined to be activated carbon from the desiccant canister inside the bottle.
  • Class III · TerminatedApr 29, 2022
    SUN PHARMACEUTICAL INDUSTRIES INCPresence Of Foreign Substance: Customer complaint for the presence of dark, gritty substance found within the bottle which was determined to be activated carbon from the desiccant canister inside the bottle.
  • Class III · TerminatedDec 20, 2016
    Sun Pharmaceutical Industries, Inc.Failed Dissolution Specifications; 18 month stability time point
  • Class III · TerminatedSep 13, 2016
    Sun Pharmaceutical Industries, Inc.Failed Dissolution Specifications
  • Class III · TerminatedJun 27, 2016
    Sun Pharmaceutical Industries, Inc.Failed Dissolution Specifications
  • Class III · TerminatedJul 17, 2015
    Sun Pharma Global FzeFailed Dissolution Specification: During analysis of the 18 month long term stability testing, it was noticed that the drug release results at the 4 hour time point are not meeting specifications.

Manufacturers of Bupropion hydrochloride (Tablet, Film Coated, Extended Release)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Aphena Pharma Solutions - Tennessee, LLCBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 3, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 3, 2026
Dr. Reddys Laboratories Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 3, 2026
Dr. Reddys Laboratories Inc.BUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 3, 2026
Proficient Rx LPBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Remedyrepack Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 3, 2026
Remedyrepack Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
ScieGen Pharmaceuticals, Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 3, 2026
Upsher-Smith Laboratories, LLCBUPROPION HYDROCHLORIDE 450 mg/1Jul 15, 2026Sep 3, 2026
A-S Medication SolutionsBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Actavis Pharma, Inc.BUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Actavis Pharma, Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Advanced Rx of Tennessee, LLCBUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Amneal Pharmaceuticals of New York LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Aphena Pharma Solutions - Tennessee, LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Asclemed USA, Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 300 mg/1Aug 5, 2026Sep 2, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Cardinal Health 107, LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA., Inc.BUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026
Cipla USA., Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Dr Reddys Laboratories IncBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Dr Reddys Laboratories IncBUPROPION HYDROCHLORIDE 300 mg/1Jul 15, 2026Sep 2, 2026
Epic Pharma, LLCBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.BUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.BUPROPION HYDROCHLORIDE 200 mg/1Jul 15, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsBUPROPION HYDROCHLORIDE 100 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsBUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals, Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals,Inc.BUPROPION HYDROCHLORIDE 150 mg/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Bupropion hydrochloride — NDC 47335-0736-86," retrieved September 3, 2026, https://drugdashboards.com/drug/47335073686.

Free to cite with attribution — see how the data is put together.