DrugDashboards

Advair Diskus

fluticasone propionate and salmeterol · SALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 500 ug/1 · Powder · Respiratory (Inhalation) · A-S Medication Solutions

NDC 50090-4505-00 · 1 INHALER in 1 CARTON / 60 POWDER in 1 INHALER · NDA · View full market →

The short version

12 companies supply this market — deep enough that no single failure threatens the supply.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00054-0328-56) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$2.27per unit
middle half $1.81$2.70 · 5,107 plans · Apr 1, 2026
Est. net of rebates
$1.36–$1.70
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
93%of plans cover it
tier 3 · prior auth 0% · step therapy 0% · qty limit 99%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for fluticasone propionate and salmeterol (other) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Regulatory

Application
NDA021077
TE code
AB
Approval date
Aug 24, 2000
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of fluticasone propionate and salmeterol (Powder)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsFLUTICASONE PROPIONATE 100 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
A-S Medication SolutionsFLUTICASONE PROPIONATE 250 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackFLUTICASONE PROPIONATE 250 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
GlaxoSmithKline LLCSALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 100 ug/1Aug 26, 2026Sep 2, 2026
GlaxoSmithKline LLCSALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 500 ug/1Aug 26, 2026Sep 2, 2026
GlaxoSmithKline LLCSALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 250 ug/1Aug 26, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.SALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 100 ug/1Aug 26, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.SALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 500 ug/1Aug 26, 2026Sep 2, 2026
Hikma Pharmaceuticals USA Inc.SALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 250 ug/1Aug 26, 2026Sep 2, 2026
Lannett Company, Inc.SALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 250 ug/1Aug 26, 2026Sep 2, 2026
Lannett Company, Inc.SALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 100 ug/1Aug 26, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.FLUTICASONE PROPIONATE 250 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.FLUTICASONE PROPIONATE 100 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.FLUTICASONE PROPIONATE 500 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
Prasco LaboratoriesFLUTICASONE PROPIONATE 100 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
Prasco LaboratoriesFLUTICASONE PROPIONATE 250 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
Prasco LaboratoriesFLUTICASONE PROPIONATE 500 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals Inc.SALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 250 ug/1Aug 26, 2026Sep 2, 2026
Preferred Pharmaceuticals Inc.SALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 100 ug/1Aug 26, 2026Sep 2, 2026
Proficient Rx LPFLUTICASONE PROPIONATE 250 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.SALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 250 ug/1Aug 26, 2026Sep 2, 2026
Remedyrepack Inc.FLUTICASONE PROPIONATE 500 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.SALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 100 ug/1Aug 26, 2026Sep 2, 2026
Teva Pharmaceuticals USA, Inc.FLUTICASONE PROPIONATE 100 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
Teva Pharmaceuticals USA, Inc.FLUTICASONE PROPIONATE 500 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
Teva Pharmaceuticals USA, Inc.FLUTICASONE PROPIONATE 250 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Sep 2, 2026
A-S Medication SolutionsSALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 500 ug/1Aug 26, 2026Aug 31, 2026
A-S Medication SolutionsSALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 100 ug/1Aug 26, 2026Aug 31, 2026
A-S Medication SolutionsSALMETEROL XINAFOATE 50 ug/1; FLUTICASONE PROPIONATE 250 ug/1Aug 26, 2026Aug 31, 2026
A-S Medication SolutionsFLUTICASONE PROPIONATE 500 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Aug 30, 2026
Remedyrepack Inc.FLUTICASONE PROPIONATE 100 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Aug 30, 2026
Remedyrepack Inc.FLUTICASONE PROPIONATE 250 ug/1; SALMETEROL XINAFOATE 50 ug/1Jul 15, 2026Aug 30, 2026
Cipla USA Inc.FLUTICASONE PROPIONATE 100 ug/1; SALMETEROL XINAFOATE 50 ug/1Aug 1, 2026Aug 29, 2026
Cipla USA Inc.FLUTICASONE PROPIONATE 250 ug/1; SALMETEROL XINAFOATE 50 ug/1Aug 1, 2026Aug 29, 2026
Cipla USA Inc.FLUTICASONE PROPIONATE 500 ug/1; SALMETEROL XINAFOATE 50 ug/1Aug 1, 2026Aug 29, 2026
A-S Medication SolutionsSALMETEROL XINAFOATE 100 ug/1; FLUTICASONE PROPIONATE 50 ug/1Jul 22, 2026Aug 22, 2026
A-S Medication SolutionsSALMETEROL XINAFOATE 250 ug/1; FLUTICASONE PROPIONATE 50 ug/1Jul 22, 2026Aug 22, 2026
A-S Medication SolutionsSALMETEROL XINAFOATE 500 ug/1; FLUTICASONE PROPIONATE 50 ug/1Jul 22, 2026Aug 20, 2026
GlaxoSmithKline LLCSALMETEROL XINAFOATE 500 ug/1; FLUTICASONE PROPIONATE 50 ug/1Jul 22, 2026Aug 19, 2026
GlaxoSmithKline LLCSALMETEROL XINAFOATE 250 ug/1; FLUTICASONE PROPIONATE 50 ug/1Jul 22, 2026Aug 19, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Advair Diskus — NDC 50090-4505-00," retrieved September 3, 2026, https://drugdashboards.com/drug/50090450500.

Free to cite with attribution — see how the data is put together.