DrugDashboards

Loperamide Hydrochloride

loperamide hydrochloride · LOPERAMIDE HYDROCHLORIDE 2 mg/1 · Capsule · Oral · Mylan Institutional Inc.

NDC 51079-0690-20 · 100 BLISTER PACK in 1 CARTON / 1 CAPSULE in 1 BLISTER PACK · ANDA · View full market →

The short version

29 companies supply this market — deep enough that no single failure threatens the supply. The price has fallen 51% in a year, to $0.0565 per unit — and generics that get this cheap tend to get abandoned rather than defended. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.0565per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Federal contracts pay (FSS)$54.75per package of 100UDMylan Institutional, Inc. · Dec 28, 2017

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00093-0311-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.2378per unit
middle half $0.2091$0.2855 · 5,381 plans · Apr 1, 2026
Est. net of rebates
≈ $0.2378
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
98%of plans cover it
tier 2 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

$0$0.2$0.4Nov 2013Sep 2026$0.0565
154 price points · per EASource: CMS NADAC

Estimated fill cost

#30 count
$1.69
#90 count
$5.08

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$823
283 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

15Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • price down 44% year over year+15

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for loperamide hydrochloride (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
ANDA072741
TE code
AB
Approval date
Sep 18, 1991
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of loperamide hydrochloride (Capsule)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 3, 2026
Aphena Pharma Solutions - Tennessee, LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 3, 2026
Cardinal Health 107, LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 3, 2026
NuCare Pharmaceuticals,Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 3, 2026
Advagen Pharma Ltd.,LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
allphamed Pharbil Arzneimittel GmbHLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
AvPAKLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Bionpharma Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Coupler LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Edenbridge Pharmaceuticals LLC.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Golden State Medical Supply, Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Mylan Institutional Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
NCS HealthCare of KY, LLC dba Vangard LabsLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
NorthStar Rx LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals, Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Redpharm DrugLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Safecor Health LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Teva Pharmaceuticals USA, Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Viona Pharmaceuticals IncLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Yyba CorpLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Zydus Lifesciences LimitedLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Aug 31, 2026
Patheon Softgels Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Aug 31, 2026
PD-Rx Pharmaceuticals, Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Aug 31, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Loperamide Hydrochloride — NDC 51079-0690-20," retrieved September 3, 2026, https://drugdashboards.com/drug/51079069020.

Free to cite with attribution — see how the data is put together.