DrugDashboards

WELMATE Anti Diarrheal Loperamide HCl Softgels

Loperamide Hydrochloride · LOPERAMIDE HYDROCHLORIDE 2 mg/1 · Capsule · Oral · Yyba Corp

NDC 73581-0102-24 · 2 BLISTER PACK in 1 CARTON / 12 CAPSULE in 1 BLISTER PACK · NDA · View full market →

The short version

29 companies supply this market — deep enough that no single failure threatens the supply.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 00093-0311-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of sale
$0.2378per unit
middle half $0.2091$0.2855 · 5,381 plans · Apr 1, 2026
Est. net of rebates
$0.1427–$0.1784
brand drug — est. 25-40% rebate off the price at left
Coverage & restrictions
98%of plans cover it
tier 2 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for loperamide hydrochloride (oral solid) in the next 90 days

sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
NDA021855
TE code
Approval date
Aug 4, 2005
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Loperamide Hydrochloride (Capsule)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 3, 2026
Aphena Pharma Solutions - Tennessee, LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 3, 2026
Cardinal Health 107, LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 3, 2026
NuCare Pharmaceuticals,Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 3, 2026
Advagen Pharma Ltd.,LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
allphamed Pharbil Arzneimittel GmbHLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
American Health PackagingLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Aurobindo Pharma LimitedLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
AvPAKLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Bionpharma Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Coupler LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Edenbridge Pharmaceuticals LLC.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Golden State Medical Supply, Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Major PharmaceuticalsLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Mylan Institutional Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Mylan Pharmaceuticals Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
NCS HealthCare of KY, LLC dba Vangard LabsLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
NorthStar Rx LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
NuCare Pharmaceuticals, Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Redpharm DrugLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Remedyrepack Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Safecor Health LLCLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Teva Pharmaceuticals USA, Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Viona Pharmaceuticals IncLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Yyba CorpLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Zydus Lifesciences LimitedLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Sep 2, 2026
Bryant Ranch PrepackLOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Aug 31, 2026
Patheon Softgels Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Aug 31, 2026
PD-Rx Pharmaceuticals, Inc.LOPERAMIDE HYDROCHLORIDE 2 mg/1Jul 15, 2026Aug 31, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "WELMATE Anti Diarrheal Loperamide HCl Softgels — NDC 73581-0102-24," retrieved September 3, 2026, https://drugdashboards.com/drug/73581010224.

Free to cite with attribution — see how the data is put together.