DrugDashboards

Butalbital, Acetaminophen and Caffeine

Butalbital, Acetaminophen, and Caffeine · BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 · Tablet · Oral · American Health Packaging

NDC 60687-0672-65 · 50 BLISTER PACK in 1 CARTON / 1 TABLET in 1 BLISTER PACK · ANDA · View full market →

The short version

17 companies supply this market — deep enough that no single failure threatens the supply. The price is down 17% over the past year, to $0.1234 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.1234per EAinvoice-surveyed acquisition cost · Jul 22, 2026
  • Medicaid generic ceiling (FUL)$0.1233per TABweighted avg manufacturer price $0.0573 · Aug 1, 2026100% of what pharmacies pay — a deeper discount than 90% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.1$0.2Nov 2022Sep 2026$0.1234
46 price points · per EA · held since Invalid Date · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$3.70
#90 count
$11.11

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$220
171 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

0● Low risk

Nothing here is signaling trouble: several manufacturers, no current shortage, no recent serious recalls, stable pricing. In drug supply, boring is the good outcome.

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for butalbital, acetaminophen and caffeine (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
ANDA040511
TE code
—
Approval date
Aug 27, 2003
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Butalbital, Acetaminophen, and Caffeine (Tablet)

LabelerStrengthFirst seenLast seen
A-S Medication SolutionsBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Actavis Pharma, Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Advanced Rx of Tennessee, LLCBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Asclemed USA, Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
AvPAKBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Cardinal Health 107, LLCBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Hawaii Repack, Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Lannett Company, Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Lgm Pharma Solutions, LlcBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Major PharmaceuticalsBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
NuCare Pharmaceuticals, Inc.ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Strides Pharma Science LimitedBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Westminster Pharmaceuticals, LLCBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Bryant Ranch PrepackBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Aug 31, 2026
Proficient Rx LPBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Aug 31, 2026
Remedyrepack Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Aug 28, 2026
Bryant Ranch PrepackBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 22, 2026
Proficient Rx LPBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 22, 2026
A-S Medication SolutionsBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Actavis Pharma, Inc.BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Advanced Rx of Tennessee, LLCBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Asclemed USA, Inc.BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
AvPAKBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Cardinal Health 107, LLCBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Hawaii Repack, Inc.BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Lannett Company, Inc.BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Lgm Pharma Solutions, LlcBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Major PharmaceuticalsBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Preferred Pharmaceuticals Inc.BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Remedyrepack Inc.BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Strides Pharma Science LimitedBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Westminster Pharmaceuticals, LLCBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
American Health PackagingBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Jul 29, 2026
Bryant Ranch PrepackACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 19, 2026
Proficient Rx LPACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 19, 2026
Remedyrepack Inc.ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 19, 2026
A-S Medication SolutionsACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026
Actavis Pharma, Inc.ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026
Advanced Rx of Tennessee, LLCACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Butalbital, Acetaminophen and Caffeine — NDC 60687-0672-65," retrieved September 3, 2026, https://drugdashboards.com/drug/60687067265.

Free to cite with attribution — see how the data is put together.