The short version
17 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Butalbital, Acetaminophen, and Caffeine
Butalbital, Acetaminophen, and Caffeine · ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1 · Tablet · Oral · NuCare Pharmaceuticals, Inc.
NDC 68071-3249-00 · 10 TABLET in 1 BOTTLE · ANDA · View full market →
Medicare Part D
No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.
How Part D pricing works →NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for butalbital, acetaminophen and caffeine (oral solid) in the next 90 days
OAI inspection at a producing facility (24 months) · sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- NuCare Pharmaceuticals,Inc.United Statesrepack
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Is this a "specialty" drug?
There's no legal definition — it meets 1 of 6 public criteria. Why that matters →
- Part D specialty tier
- Costs ≥ $950/fill
- Biologic (BLA)
- Injectable / infused
- Orphan-drug exclusivity
- REMS program · Opioid Analgesic REMS Shared System REMS
Regulatory
- Application
- ANDA200243
- TE code
- AA
- Approval date
- Sep 13, 2012
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Butalbital, Acetaminophen, and Caffeine (Tablet)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| A-S Medication Solutions | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Actavis Pharma, Inc. | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Advanced Rx of Tennessee, LLC | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Asclemed USA, Inc. | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| AvPAK | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Cardinal Health 107, LLC | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Hawaii Repack, Inc. | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Lannett Company, Inc. | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Lgm Pharma Solutions, Llc | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals, Inc. | ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals Inc. | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Strides Pharma Science Limited | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Westminster Pharmaceuticals, LLC | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Aug 31, 2026 |
| Proficient Rx LP | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Aug 31, 2026 |
| Remedyrepack Inc. | BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1 | Aug 26, 2026 | Aug 28, 2026 |
| Bryant Ranch Prepack | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| Proficient Rx LP | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| A-S Medication Solutions | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Actavis Pharma, Inc. | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Advanced Rx of Tennessee, LLC | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Asclemed USA, Inc. | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| AvPAK | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Cardinal Health 107, LLC | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Hawaii Repack, Inc. | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Lannett Company, Inc. | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Lgm Pharma Solutions, Llc | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Major Pharmaceuticals | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Preferred Pharmaceuticals Inc. | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Remedyrepack Inc. | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Strides Pharma Science Limited | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Westminster Pharmaceuticals, LLC | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| American Health Packaging | BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1 | Jul 22, 2026 | Jul 29, 2026 |
| Bryant Ranch Prepack | ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| Proficient Rx LP | ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| Remedyrepack Inc. | ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| A-S Medication Solutions | ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Actavis Pharma, Inc. | ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Advanced Rx of Tennessee, LLC | ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Butalbital, Acetaminophen, and Caffeine — NDC 68071-3249-00," retrieved September 3, 2026, https://drugdashboards.com/drug/68071324900.
Free to cite with attribution — see how the data is put together.