DrugDashboards

Diphenhydramine HCl Oral Solution

diphenhydramine hydrochloride · DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/10mL · Solution · Oral · Natco Pharma USA LLC

NDC 69339-0152-17 · 4 TRAY in 1 CASE / 10 CUP, UNIT-DOSE in 1 TRAY / 10 mL in 1 CUP, UNIT-DOSE · OTC MONOGRAPH DRUG · View full market →

The short version

26 companies supply this market — deep enough that no single failure threatens the supply.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

Medicare Part D does not cover over-the-counter drugs — by law it pays only for products requiring a prescription.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed
$97.20
Reported to Texas DSHS · 2026 annual filing · Natco Pharma USA

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicaid spend (2025)

$594
609 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for diphenhydramine hydrochloride (other) in the next 90 days

sole-source market · price up 9% YoY

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Regulatory

Application
M012
TE code
—
Approval date
—
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of diphenhydramine hydrochloride (Solution)

LabelerStrengthFirst seenLast seen
Kenvue Brands LLCDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 3, 2026
PAI Holdings, LLC dba PAI PharmaDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 3, 2026
PAI Holdings, LLC dba PAI PharmaDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/10mLJul 15, 2026Sep 3, 2026
American Health PackagingDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/10mLJul 15, 2026Sep 2, 2026
American Health PackagingDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Amerisource BergenDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Camber Pharmaceuticals, Inc.DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/10mLJul 15, 2026Sep 2, 2026
Dolgencorp, LLCDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Foundation Consumer HealthcareDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/10mLJul 15, 2026Sep 2, 2026
Kroger CompanyDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Major PharmaceuticalsDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Major PharmaceuticalsDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/10mLJul 15, 2026Sep 2, 2026
Medical Purchasing Solutions, LLCDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/10mLJul 15, 2026Sep 2, 2026
Meijer Distribution IncDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Meijer Distribution IncDIPHENHYDRAMINE HYDROCHLORIDE 50 mg/30mLJul 15, 2026Sep 2, 2026
Natco Pharma USA LLCDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Natco Pharma USA LLCDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/10mLJul 15, 2026Sep 2, 2026
Oncor PharmaceuticalsDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Preferred Pharmaceuticals Inc.DIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Proficient Rx LPDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Quality Choice (Chain Drug Marketing Association)DIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Redmont Pharmaceuticals, LLCDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLAug 5, 2026Sep 2, 2026
Strategic Sourcing Services LLCDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Target CorporationDIPHENHYDRAMINE HYDROCHLORIDE 50 mg/30mLJul 15, 2026Sep 2, 2026
Topco Associates LLCDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Wal-Mart Stores IncDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Wal-Mart Stores Inc.DIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Walgreen CompanyDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026
Walgreen CompanyDIPHENHYDRAMINE HYDROCHLORIDE 50 mg/30mLJul 15, 2026Sep 2, 2026
Walgreen CompanyDIPHENHYDRAMINE HYDROCHLORIDE 25 mg/10mLJul 15, 2026Sep 2, 2026
Winco Foods, LlcDIPHENHYDRAMINE HYDROCHLORIDE 12.5 mg/5mLJul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Diphenhydramine HCl Oral Solution — NDC 69339-0152-17," retrieved September 3, 2026, https://drugdashboards.com/drug/69339015217.

Free to cite with attribution — see how the data is put together.