loperamide hydrochloride · LOPERAMIDE HYDROCHLORIDE 2 mg/1 · Capsule · Oral · Bionpharma Inc.
NDC 69452-0271-30 · 500 CAPSULE in 1 BOTTLE, PLASTIC · ANDA · View full market →
29 companies supply this market — deep enough that no single failure threatens the supply. The price has fallen 51% in a year, to $0.0565 per unit — and generics that get this cheap tend to get abandoned rather than defended. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Matched to CMS's representative package for this drug (NDC 00093-0311-01) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.
Some pressure is visible, but not much — here’s everything the score found to count.
The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
No FDA shortage reports for this drug or its presentations.
No enforcement reports list this package NDC.
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| A-S Medication Solutions | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Aphena Pharma Solutions - Tennessee, LLC | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Cardinal Health 107, LLC | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| NuCare Pharmaceuticals,Inc. | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 3, 2026 |
| Advagen Pharma Ltd., | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| allphamed Pharbil Arzneimittel GmbH | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| American Health Packaging | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Aurobindo Pharma Limited | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| AvPAK | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Bionpharma Inc. | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Coupler LLC | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Edenbridge Pharmaceuticals LLC. | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Golden State Medical Supply, Inc. | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Major Pharmaceuticals | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Mylan Institutional Inc. | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Mylan Pharmaceuticals Inc. | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NCS HealthCare of KY, LLC dba Vangard Labs | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NorthStar Rx LLC | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| NuCare Pharmaceuticals, Inc. | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Redpharm Drug | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Remedyrepack Inc. | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Safecor Health LLC | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Teva Pharmaceuticals USA, Inc. | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Viona Pharmaceuticals Inc | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Yyba Corp | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Zydus Lifesciences Limited | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Bryant Ranch Prepack | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Aug 31, 2026 |
| Patheon Softgels Inc. | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Aug 31, 2026 |
| PD-Rx Pharmaceuticals, Inc. | LOPERAMIDE HYDROCHLORIDE 2 mg/1 | Jul 15, 2026 | Aug 31, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
DrugDashboards, "Loperamide Hydrochloride — NDC 69452-0271-30," retrieved September 3, 2026, https://drugdashboards.com/drug/69452027130.
Free to cite with attribution — see how the data is put together.