DrugDashboards

Butalbital, Acetaminophen and Caffeine

Butalbital, Acetaminophen and Caffeine · BUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1 · Capsule · Oral · Granules Pharmaceuticals Inc.

NDC 70010-0044-01 · 100 CAPSULE in 1 BOTTLE · ANDA · View full market →

The short version

12 companies supply this market — deep enough that no single failure threatens the supply. The price is down 30% over the past year, to $0.3161 per unit. Put together: this looks like a healthy supply — the boring kind, which is exactly what you want.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built
Data sources
  • CMS NADAC (pharmacy acquisition, weekly)
  • CMS Part B ASP quarterly payment limits
  • CMS Maximum Fair Prices (IRA negotiated, NDC-level)
  • Medicare Part D Spending by Drug (data.cms.gov, name-matched)
  • VA FSS / Big4 federal contract prices (va.gov, twice monthly)
  • ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
  • California SB-17 WAC filings (list price, per package)
Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

  • Pharmacies pay (NADAC)$0.3161per EAinvoice-surveyed acquisition cost · Aug 19, 2026
  • Medicaid generic ceiling (FUL)$0.5046per CAPweighted avg manufacturer price $0.2756 · Aug 1, 2024160% of what pharmacies pay — higher than 81% of drugs with this benchmark

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

$0$0.5$1.00$1.50Jul 2020Sep 2026$0.3161
75 price points · per EA · dashed = manufacturer avg (WAMP)Source: CMS NADAC

Estimated fill cost

#30 count
$9.48
#90 count
$28.45

Estimates: latest NADAC unit price × quantity. Pharmacy acquisition cost only — excludes dispensing fees, markup, and insurance terms.

Medicaid spend (2025)

$225,979
8,483 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

8● Low risk

Some pressure is visible, but not much — here’s everything the score found to count.

  • price down 30% year over year+8

The score counts pressure that is already visible — fewer makers, shortages, recalls, falling prices. 0 means none of it; 100 means all of it at once. Recomputed daily · as of Sep 3, 2026

90-day shortage risk (model v2)

0.1%chance of a new FDA shortage posting for butalbital, acetaminophen and caffeine (oral solid) in the next 90 days

OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application
ANDA213321
TE code
AA
Approval date
Apr 8, 2020
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Butalbital, Acetaminophen and Caffeine (Capsule)

LabelerStrengthFirst seenLast seen
Bryant Ranch PrepackBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 3, 2026
Bryant Ranch PrepackACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1; BUTALBITAL 50 mg/1Aug 26, 2026Sep 3, 2026
Advanced Rx of Tennessee, LLCBUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Amici Pharma, Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Aurolife Pharma, LLCBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Dr. Reddy's Labratories Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Granules Pharmaceuticals Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Lannett Company, Inc.BUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Mayne PharmaBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Quagen Pharmaceuticals LlcBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Quagen Pharmaceuticals LlcBUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Seton Pharmaceuticals LLCBUTALBITAL 50 mg/1; ACETAMINOPHEN 325 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Seton Pharmaceuticals LLCBUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Solco Healthcare Us, LlcBUTALBITAL 50 mg/1; ACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1Aug 26, 2026Sep 2, 2026
Sunrise Pharmaceutical, IncACETAMINOPHEN 300 mg/1; CAFFEINE 40 mg/1; BUTALBITAL 50 mg/1Aug 26, 2026Sep 2, 2026
Bryant Ranch PrepackBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 22, 2026
Bryant Ranch PrepackACETAMINOPHEN 300 mg/1; CAFFEINE 50 mg/1; BUTALBITAL 40 mg/1Jul 22, 2026Aug 21, 2026
Advanced Rx of Tennessee, LLCBUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Amici Pharma, Inc.BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Aurolife Pharma, LLCBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Dr. Reddy's Labratories Inc.BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Granules Pharmaceuticals Inc.BUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Lannett Company, Inc.BUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Mayne PharmaBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Quagen Pharmaceuticals LlcBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Quagen Pharmaceuticals LlcBUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Seton Pharmaceuticals LLCBUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Seton Pharmaceuticals LLCBUTALBITAL 325 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Solco Healthcare Us, LlcBUTALBITAL 300 mg/1; ACETAMINOPHEN 50 mg/1; CAFFEINE 40 mg/1Jul 22, 2026Aug 19, 2026
Sunrise Pharmaceutical, IncACETAMINOPHEN 300 mg/1; CAFFEINE 50 mg/1; BUTALBITAL 40 mg/1Jul 22, 2026Aug 19, 2026
Bryant Ranch PrepackACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 19, 2026
Bryant Ranch PrepackACETAMINOPHEN 300 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 19, 2026
Advanced Rx of Tennessee, LLCACETAMINOPHEN 300 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026
Amici Pharma, Inc.ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026
Aurolife Pharma, LLCACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026
Dr. Reddy's Labratories Inc.ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026
Granules Pharmaceuticals Inc.ACETAMINOPHEN 300 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026
Lannett Company, Inc.ACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026
Mayne PharmaACETAMINOPHEN 325 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026
Quagen Pharmaceuticals LlcACETAMINOPHEN 300 mg/1; BUTALBITAL 50 mg/1; CAFFEINE 40 mg/1Jul 15, 2026Jul 15, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Butalbital, Acetaminophen and Caffeine — NDC 70010-0044-01," retrieved September 3, 2026, https://drugdashboards.com/drug/70010004401.

Free to cite with attribution — see how the data is put together.