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piperacillin and tazobactam

piperacillin and tazobactam · PIPERACILLIN SODIUM 2 g/10mL; TAZOBACTAM SODIUM .25 g/10mL · Injection, Powder, For Solution · Intravenous · Onesource Specialty Pharma Limited

NDC 83270-0301-10 · 10 VIAL, SINGLE-USE in 1 CARTON / 10 mL in 1 VIAL, SINGLE-USE · ANDA · View full market →

The short version

9 companies supply this market — a reasonable cushion if one runs into trouble. Historically, drugs in this position went on to a new shortage within 90 days about 0.4% of the time — roughly 3× the typical drug (0.1%).

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

Medicare Part D

All Part D pricing →

Matched to CMS's representative package for this drug (NDC 60505-6156-04) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.

ⓘ How this was built
Data sources
  • CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method

Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Plans pay at point of saleⓘ
$5.40per unit
middle half $3.98–$6.63 · 5,474 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $5.40
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
100%of plans cover it
tier 4 · prior auth 0% · step therapy 0% · qty limit 0%

*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.4%chance of a new FDA shortage posting for piperacillin and tazobactam (injectable) in the next 90 days

sterile injectable · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 3× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 1 of 6 public criteria. Why that matters →

  • Part D specialty tier
  • Costs ≥ $950/fill
  • Biologic (BLA)
  • Injectable / infused
  • Orphan-drug exclusivity
  • REMS program

Regulatory

Application
ANDA065458
TE code
AP
Approval date
Aug 15, 2014
Patents / exclusivity
None on file

Shortage history

No FDA shortage reports for this drug or its presentations.

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of piperacillin and tazobactam (Injection, Powder, For Solution)

LabelerStrengthFirst seenLast seen
Fresenius Kabi USA, LLCPIPERACILLIN SODIUM 36 g/180mL; TAZOBACTAM SODIUM 4.5 g/180mLJul 15, 2026Sep 3, 2026
Apotex Corp.PIPERACILLIN SODIUM 3 g/15mL; TAZOBACTAM SODIUM .375 g/15mLJul 15, 2026Sep 2, 2026
Apotex Corp.PIPERACILLIN SODIUM 4 g/20mL; TAZOBACTAM SODIUM .5 g/20mLJul 15, 2026Sep 2, 2026
Apotex Corp.PIPERACILLIN SODIUM 2 g/10mL; TAZOBACTAM SODIUM .25 g/10mLJul 15, 2026Sep 2, 2026
Armas Pharmaceuticals Inc.PIPERACILLIN SODIUM 3 g/15mL; TAZOBACTAM SODIUM .375 g/15mLJul 15, 2026Sep 2, 2026
Armas Pharmaceuticals Inc.PIPERACILLIN SODIUM 4 g/20mL; TAZOBACTAM SODIUM .5 g/20mLJul 15, 2026Sep 2, 2026
Avenacy, LLCPIPERACILLIN SODIUM 2 g/10mL; TAZOBACTAM SODIUM .25 g/10mLJul 15, 2026Sep 2, 2026
Avenacy, LLCPIPERACILLIN SODIUM 36 g/180mL; TAZOBACTAM SODIUM 4.5 g/180mLJul 15, 2026Sep 2, 2026
Avenacy, LLCPIPERACILLIN SODIUM 3 g/15mL; TAZOBACTAM SODIUM .375 g/15mLJul 15, 2026Sep 2, 2026
Avenacy, LLCPIPERACILLIN SODIUM 4 g/20mL; TAZOBACTAM SODIUM .5 g/20mLJul 15, 2026Sep 2, 2026
BluePoint LaboratoriesPIPERACILLIN SODIUM 2 g/10mL; TAZOBACTAM SODIUM .25 g/10mLJul 15, 2026Sep 2, 2026
BluePoint LaboratoriesPIPERACILLIN SODIUM 3 g/15mL; TAZOBACTAM SODIUM .375 g/15mLJul 15, 2026Sep 2, 2026
BluePoint LaboratoriesPIPERACILLIN SODIUM 4 g/20mL; TAZOBACTAM SODIUM .5 g/20mLJul 15, 2026Sep 2, 2026
Civica, Inc.PIPERACILLIN SODIUM 4 g/20mL; TAZOBACTAM SODIUM .5 g/20mLJul 15, 2026Sep 2, 2026
Civica, Inc.PIPERACILLIN SODIUM 3 g/15mL; TAZOBACTAM SODIUM .375 g/15mLJul 15, 2026Sep 2, 2026
Onesource Specialty Pharma LimitedPIPERACILLIN SODIUM 2 g/10mL; TAZOBACTAM SODIUM .25 g/10mLJul 15, 2026Sep 2, 2026
Onesource Specialty Pharma LimitedPIPERACILLIN SODIUM 3 g/15mL; TAZOBACTAM SODIUM .375 g/15mLJul 15, 2026Sep 2, 2026
Onesource Specialty Pharma LimitedPIPERACILLIN SODIUM 4 g/20mL; TAZOBACTAM SODIUM .5 g/20mLJul 15, 2026Sep 2, 2026
Shandong Anxin Pharmaceutical Co., Ltd.PIPERACILLIN SODIUM 3 g/15mL; TAZOBACTAM SODIUM .375 g/15mLJul 15, 2026Sep 2, 2026
Shandong Anxin Pharmaceutical Co., Ltd.PIPERACILLIN SODIUM 2 g/10mL; TAZOBACTAM SODIUM .25 g/10mLJul 15, 2026Sep 2, 2026
Shandong Anxin Pharmaceutical Co., Ltd.PIPERACILLIN SODIUM 4 g/20mL; TAZOBACTAM SODIUM .5 g/20mLJul 15, 2026Sep 2, 2026
WG Critical Care, LLCPIPERACILLIN SODIUM 36 g/1; TAZOBACTAM SODIUM 4.5 g/1Jul 15, 2026Sep 2, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "piperacillin and tazobactam — NDC 83270-0301-10," retrieved September 3, 2026, https://drugdashboards.com/drug/83270030110.

Free to cite with attribution — see how the data is put together.