The short version
11 companies supply this market — deep enough that no single failure threatens the supply.
The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.
Naproxen and esomeprazole magnesium
Naproxen and esomeprazole magnesium · NAPROXEN 375 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 · Tablet, Delayed Release · Oral · Phoenix Rx Llc
NDC 85509-1202-03 · 30 TABLET, DELAYED RELEASE in 1 BOTTLE · ANDA · View full market →
Medicare Part D
All Part D pricing →Matched to CMS's representative package for this drug (NDC 55111-0289-60) — same generic, strength, and dosage form. CMS prices one NDC per drug concept, not every package.
ⓘ How this was built
Data sources
- CMS quarterly Prescription Drug Plan Formulary & Pricing files (SPUF)
Method
Negotiated 30-day point-of-sale unit prices and formulary terms aggregated across every unsuppressed Part D and MA-PD plan for the quarter shown. Point of sale means gross of confidential rebates. CMS publishes one representative NDC per drug concept (RxCUI) rather than every package, so these figures come from CMS's representative package for the same drug — matched on generic name, strength, and dosage form. Estimated from MedPAC's program-wide rebate aggregates (June 2023: DIR = 29% of gross Part D spending; brand rebates ≈ 25–40% of gross, generics minimal). Actual rebates are confidential and vary widely by drug — this is a range, not a fact about this drug.
Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.
Plans pay at point of saleⓘ
$9.48per unit
middle half $8.18–$9.48 · 27 plans · Apr 1, 2026
Est. net of rebatesⓘ
≈ $9.48
generic — rebates are minimal, so net ≈ gross
Coverage & restrictions
0%of plans cover it
tier 4 · prior auth 100% · step therapy 0% · qty limit 100%
*No drug-level rebate is public — the estimate applies MedPAC's program-wide brand rebate range to this drug's gross price. Tracked here for 10 quarters since 2024.
NADAC price per unit
No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.
Supply fragility
Not scored — fragility is computed for NADAC-priced NDCs.
90-day shortage risk (model v2)
0.1%chance of a new FDA shortage posting for naproxen and esomeprazole magnesium (oral solid) in the next 90 days
sole-source market
For scale: the typical drug’s chance is about 0.1% — this one is in ordinary territory.
Backtested statistical model over the whole market, not this package alone. Model details →
Where it's made
- Phoenix Rx LlcUnited Statesrelabel · repack
Establishments this product's FDA label declares, located via FDA registration data. How we built this →
Regulatory
- Application
- ANDA213699
- TE code
- AB
- Approval date
- Oct 6, 2022
- Patents / exclusivity
- None on file
Shortage history
No FDA shortage reports for this drug or its presentations.
Recalls (this NDC)
No enforcement reports list this package NDC.
Manufacturers of Naproxen and esomeprazole magnesium (Tablet, Delayed Release)
| Labeler | Strength | First seen | Last seen |
|---|---|---|---|
| Bryant Ranch Prepack | NAPROXEN 500 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Sep 3, 2026 |
| Ajanta Pharma USA Inc. | NAPROXEN 500 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Ajanta Pharma USA Inc. | NAPROXEN 375 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Asclemed USA, Inc. | NAPROXEN 500 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Asclemed USA, Inc. | NAPROXEN 375 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Doc Rx | NAPROXEN 500 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Dr. Reddy's Laboratories Limited | NAPROXEN 500 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Dr. Reddy's Laboratories Limited | NAPROXEN 375 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Patheon Pharmaceuticals Inc. | ESOMEPRAZOLE MAGNESIUM 20 mg/1; NAPROXEN 500 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Patheon Pharmaceuticals Inc. | ESOMEPRAZOLE MAGNESIUM 20 mg/1; NAPROXEN 375 mg/1 | Jul 15, 2026 | Sep 2, 2026 |
| Phoenix Rx Llc | NAPROXEN 375 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals Inc | NAPROXEN 375 mg/1; ESOMEPRAZOLE MAGNESIUM TRIHYDRATE 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Preferred Pharmaceuticals Inc. | NAPROXEN 375 mg/1; ESOMEPRAZOLE MAGNESIUM TRIHYDRATE 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Proficient Rx LP | NAPROXEN 500 mg/1; ESOMEPRAZOLE MAGNESIUM TRIHYDRATE 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| ScieGen Pharmaceuticals, Inc | NAPROXEN 500 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| ScieGen Pharmaceuticals, Inc | NAPROXEN 375 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Sep 2, 2026 |
| Phoenix Rx Llc | NAPROXEN 500 mg/1; ESOMEPRAZOLE MAGNESIUM 20 mg/1 | Aug 26, 2026 | Aug 28, 2026 |
| Preferred Pharmaceuticals Inc. | NAPROXEN 500 mg/1; ESOMEPRAZOLE MAGNESIUM TRIHYDRATE 20 mg/1 | Aug 26, 2026 | Aug 28, 2026 |
| Bryant Ranch Prepack | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 500 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| Phoenix Rx Llc | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 500 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| Preferred Pharmaceuticals Inc. | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM TRIHYDRATE 500 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| Preferred Pharmaceuticals Inc. | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM TRIHYDRATE 375 mg/1 | Jul 25, 2026 | Aug 22, 2026 |
| Proficient Rx LP | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM TRIHYDRATE 500 mg/1 | Jul 22, 2026 | Aug 22, 2026 |
| Ajanta Pharma USA Inc. | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 500 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Ajanta Pharma USA Inc. | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 375 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Asclemed USA, Inc. | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 375 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Asclemed USA, Inc. | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 500 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Doc Rx | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 500 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Dr. Reddy's Laboratories Limited | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 375 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Dr. Reddy's Laboratories Limited | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 500 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Phoenix Rx Llc | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 375 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Preferred Pharmaceuticals Inc | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM TRIHYDRATE 375 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| ScieGen Pharmaceuticals, Inc | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 375 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| ScieGen Pharmaceuticals, Inc | NAPROXEN 20 mg/1; ESOMEPRAZOLE MAGNESIUM 500 mg/1 | Jul 22, 2026 | Aug 19, 2026 |
| Bryant Ranch Prepack | ESOMEPRAZOLE MAGNESIUM 20 mg/1; NAPROXEN 500 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| Preferred Pharmaceuticals Inc. | ESOMEPRAZOLE MAGNESIUM TRIHYDRATE 20 mg/1; NAPROXEN 500 mg/1 | Jul 15, 2026 | Jul 19, 2026 |
| Phoenix Rx Llc | ESOMEPRAZOLE MAGNESIUM 20 mg/1; NAPROXEN 500 mg/1 | Jul 15, 2026 | Jul 18, 2026 |
| Ajanta Pharma USA Inc. | ESOMEPRAZOLE MAGNESIUM 20 mg/1; NAPROXEN 500 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Ajanta Pharma USA Inc. | ESOMEPRAZOLE MAGNESIUM 20 mg/1; NAPROXEN 375 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
| Asclemed USA, Inc. | ESOMEPRAZOLE MAGNESIUM 20 mg/1; NAPROXEN 375 mg/1 | Jul 15, 2026 | Jul 15, 2026 |
Roster from daily NDC Directory diffs — first/last seen dates start July 2026.
Cite this page
DrugDashboards, "Naproxen and esomeprazole magnesium — NDC 85509-1202-03," retrieved September 3, 2026, https://drugdashboards.com/drug/85509120203.
Free to cite with attribution — see how the data is put together.