Morphine Sulfate

Morphine Sulfate · MORPHINE SULFATE 50 mg/mL · Injection, Solution · Intravenous · Hospira, Inc.

NDC 00409-1896-20 · 1 VIAL, SINGLE-DOSE in 1 CARTON / 20 mL in 1 VIAL, SINGLE-DOSE · NDA · View full market →

The short version

5 companies supply this market — a reasonable cushion if one runs into trouble. It is in shortage right now — FDA lists the reason as “discontinuation of the manufacture of the drug”.

The numbers behind every sentence are on this page below — and the Watch button emails you when any of them move.

One drug, every price

The same NDC has different prices depending on who is paying. Units differ between rungs — compare within a rung over time, not rung against rung, unless the units match.

ⓘ How this was built

Data sources

CMS NADAC (pharmacy acquisition, weekly)
CMS Part B ASP quarterly payment limits
CMS Maximum Fair Prices (IRA negotiated, NDC-level)
Medicare Part D Spending by Drug (data.cms.gov, name-matched)
VA FSS / Big4 federal contract prices (va.gov, twice monthly)
ACA Federal Upper Limits + weighted AMP (data.medicaid.gov, monthly)
California SB-17 WAC filings (list price, per package)

Method

Each rung is the newest figure for this NDC from one federal price system, shown with its own unit. Part D is matched by drug name because CMS publishes no NDCs there; it is gross spending, before confidential rebates.

Pipeline and calculations built by Claude (Fable 5) from the public datasets above. Educational only — verify against primary sources before acting.

Medicare Part B pays (ASP+6%)$8.09per billing unit (10 MG)HCPCS J2270 · Jul 1, 2026
Part D plans paid (avg)$0.5055per dosage unitgross, before rebates — matched by drug name · 2024
Federal ceiling (Big4)$14.48per package of 20MLPfizer Inc. · Jan 1, 2026
List price (WAC, as filed)$87.04per packagePfizer · Jan 1, 2026

Medicare Part D

No Medicare Part D plan in CMS's quarterly files lists this product. That usually means it is discontinued, a repackager's listing, or a product no plan has added to its formulary.

How Part D pricing works →

NADAC price per unit

No NADAC pricing on file for this NDC — NADAC covers drugs dispensed by retail community pharmacies.

Estimated fill cost

WAC per package, as filed

$21.76

Reported to Texas DSHS · 2026 annual filing · Pfizer Inc.

Manufacturer list price as filed — not what pharmacies actually pay after discounts.

Medicare Part B (ASP)

Payment limit per 10 MG

$8.087

HCPCS J2270 · Jul 1, 2026 quarter · typically ASP + 6%

Medicaid spend (2025)

$55

22 prescriptions paid by Medicaid nationally · all Medicaid spend →

Supply fragility

Not scored — fragility is computed for NADAC-priced NDCs.

90-day shortage risk (model v2)

0.5%chance of a new FDA shortage posting for morphine sulfate (injectable) in the next 90 days

sterile injectable · OAI inspection at a producing facility (24 months) · sole-source market

For scale: the typical drug’s chance is about 0.1% — this one is 4× that.

Backtested statistical model over the whole market, not this package alone. Model details →

Where it's made

Hospira, Inc.United States
analysis · label · manufacture · pack

Establishments this product's FDA label declares, located via FDA registration data. How we built this →

Is this a "specialty" drug?

There's no legal definition — it meets 2 of 6 public criteria. Why that matters →

Part D specialty tier
Costs ≥ $950/fill · avg $28.78 per prescription
Biologic (BLA)
Injectable / infused
Orphan-drug exclusivity
REMS program · Opioid Analgesic REMS Shared System REMS

Regulatory

Application: NDA202515
TE code: AP
Approval date: Nov 14, 2011
Patents / exclusivity: None on file

Shortage history

In shortage now — Infumorph 200 (Preservative-Free Morphine Sulfate Sterile Solution), Injection, 10 mg/1 mL (NDC 0641-6039-01)Nov 3, 2017
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Infumorph 500 (Preservative-Free Morphine Sulfate Sterile Solution), Injection, 25 mg/1 mL (NDC 0641-6040-01)Nov 3, 2017
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 10 mg/1 mL (NDC 63323-451-01)Oct 31, 2017
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 10 mg/1 mL Syringes (NDC 0409-1893-01)Oct 31, 2017
Discontinuation of the manufacture of the drug
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 10 mg/10 mL (1 mg/mL) (NDC 0409-3815-12)Oct 31, 2017
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 2 mg/1 mL (NDC 0409-1890-23)Oct 31, 2017
Other
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 2 mg/1 mL (NDC 63323-452-01)Oct 31, 2017
Other
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 2 mg/1 mL (NDC 76045-004-11)Oct 31, 2017
Other
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 2 mg/1 mL Syringes (NDC 0409-1890-01)Oct 31, 2017
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 4 mg/1 mL (NDC 63323-454-01)Oct 31, 2017
Other
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 4 mg/1 mL (NDC 76045-005-11)Oct 31, 2017
Other
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 4 mg/1 mL Syringes (NDC 0409-1891-01)Oct 31, 2017
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 5 mg/10 mL (0.5 mg/mL) (NDC 0409-3814-12)Oct 31, 2017
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months
In shortage now — Morphine Sulfate, Injection, 50 mg/1 mL (NDC 0409-1896-20)Oct 31, 2017
Other
month 107 — 5× the typical 20-month injectable shortage · model puts 24% odds it resolves within 6 months

Recalls (this NDC)

No enforcement reports list this package NDC.

Manufacturers of Morphine Sulfate (Injection, Solution)

Labeler	Strength	First seen	Last seen
Hospira, Inc.	MORPHINE SULFATE 50 mg/mL	Jul 15, 2026	Sep 3, 2026
Bond Pharmacy INC	MORPHINE SULFATE 62.5 mg/mL	Jul 15, 2026	Sep 2, 2026
Fresenius Kabi USA, LLC	MORPHINE SULFATE 4 mg/mL	Jul 15, 2026	Sep 2, 2026
Fresenius Kabi USA, LLC	MORPHINE SULFATE 10 mg/mL	Jul 15, 2026	Sep 2, 2026
Fresenius Kabi USA, LLC	MORPHINE SULFATE 2 mg/mL	Jul 15, 2026	Sep 2, 2026
Fresenius Kabi, USA LLC	MORPHINE SULFATE 4 mg/mL	Jul 15, 2026	Sep 2, 2026
Fresenius Kabi, USA LLC	MORPHINE SULFATE 2 mg/mL	Jul 15, 2026	Sep 2, 2026
Hikma Pharmaceuticals USA Inc.	MORPHINE SULFATE 25 mg/mL	Jul 15, 2026	Sep 2, 2026
Hikma Pharmaceuticals USA Inc.	MORPHINE SULFATE 10 mg/mL	Jul 15, 2026	Sep 2, 2026
Hospira, Inc.	MORPHINE SULFATE 2 mg/mL	Jul 15, 2026	Sep 2, 2026
Hospira, Inc.	MORPHINE SULFATE 1 mg/mL	Jul 15, 2026	Sep 2, 2026
Hospira, Inc.	MORPHINE SULFATE .5 mg/mL	Jul 15, 2026	Sep 2, 2026
Hospira, Inc.	MORPHINE SULFATE 4 mg/mL	Jul 15, 2026	Sep 2, 2026
Hospira, Inc.	MORPHINE SULFATE 10 mg/mL	Jul 15, 2026	Aug 29, 2026

Roster from daily NDC Directory diffs — first/last seen dates start July 2026.

Cite this page

DrugDashboards, "Morphine Sulfate — NDC 00409-1896-20," retrieved September 3, 2026, https://drugdashboards.com/drug/00409189620.

Free to cite with attribution — see how the data is put together.